Businesses routinely rely on econometric models to analyze and predict consumer behavior. Estimation of such models may require combining a firm’s internal data with external datasets to take into account sample selection, missing observations, omitted variables and errors in measurement within the existing data source. In this paper we point out that these data problems can be addressed when e...

(1) In order to study the relationship between the energy metabolism via TCA cycle and amino acid metabolism as well as protein synthesis, C14-labelled substrates were used for tracer experiment . (2) Considerable C14O2 formation was noted from carbohydrates such as acetate-1-C14, pyruvate-1-C14, and pyruvate-3-C14, while a smaller amount of C14O2 was produced from amino acids such as glycine1-...

Bacterial translocation occurs when viable bacteria pass through the mucosa of the gastrointestinal tract to the mesenteric lymph nodes (MLN) and other organs. The ability of a diet containing 1% culture condensate of Bifidobacterium longum (MB) to inhibit bacterial translocation from the gastrointestinal tract was tested using antibiotic-decontaminated specific-pathogen-free (SPF) mice and ger...

Protein N-myristoylation occurs by a covalent attachment of a C14:0 fatty acid to the N-terminal Gly residue. This reaction is catalyzed by a N-myristoyltransferase that uses myristoyl-coenzyme A as substrate. But proteins in the retina also undergo heterogeneous N-acylation with C14:2, C14:1, and C12:0 fatty acids. The basis and the role of this retina-specific phenomenon are poorly understood...

The synthesis of the C9-C25 subunit of the marine natural product spirastrellolide B is reported. The key synthetic features included the union of the two key fragments 5 and 6 via a Suzuki-Miyaura coupling reaction and a late-stage, one-pot sequential deprotection/cascade Achmatowicz rearrangement-spiroketalization to install the key spirocyclic intermediate present in the C9-C25 fragment of s...