Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on ∆(9)-tetrahydrocannabinol (∆(9)-THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced....

BACKGROUND In the present study the effect of Nigella sativa (N. sativa) ethanolic extract on cytokine profile in control, moderate and overtrained heavy exercised rat was examined. METHODS Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V = 20 m/min, 30 min/day, 6 days a week, for 8 weeks), overtrained (OT) (V = 25 m/min, 60 min/day, 6 days a week, ...

diabetes is a metabolic disorder inducing undesirable effects on male reproductive system. cannabis sativa (c. sativa) is a plant that affects diabetes and decreases blood glucose. the present study was aimed to investigate the effect of cannabis sativa hydroalcoholic extract on sperm parameters in diabetic rats. thirty five male wistar rats (210-240 gr) were divided into five groups: control (...

The European chestnut (Castanea sativa) is threatened by the hemibiotrophic oomycete Phytophthora cinnamomi, causal agent of ink disease. Chestnut species have different susceptibility levels to P. with Asian (C. crenata; C. mollissima) exhibiting highest level resistance. A histological approach was used study responses exhibited susceptible and resistant genotypes characterizing early stages ...

Introduction: Amphotericin B is considered as one of the most effective antifungal drugs presently used to treat systemic fungal infections; however, nephrotoxicity remains the major side effect. The current study is therefore, designed to determine Amphotericin B induced nephrotoxicity and its prevention by administration of Nigella sativa (NS) extract in albino mice. Materials and Methods: Th...

Nigella sativa (N.sativa) has been used in traditional medicine and many studies have been performed in different communities in order to reveal the effects of it on medical disorders and chronic diseases. The aim of this study was to investigate the effects of bread with N. Sativa on lipid profiles, apolipoproteins, and inflammatory factors in metabolic syndrome (MetS) patients. A randomized, ...

Objective(s): Metastasis is the main cause of death in patients with melanoma. Cannabis-based medicines are effective adjunctive drugs in cancer patients. Tau and Stathmin proteins are the key proteins in cancer metastasis. Here we have investigated the effect of a standardized Cannabis sativa extract on cell migration and Tau and Stathmin gene expression in the melanoma cell line. Materials an...

Phototransformation of phytochrome in lettuce seeds (Lactuca sativa L. var. Grand Rapids) was examined by testing germination responses of seeds irradiated at various temperatures. Temperature variations from 0 to 50 C had no influence on the germination of partially hydrated seeds (about 15% water content) irradiated with either red or far red light prior to imbibition. At -15 C far red light ...

In Iran, more than 90% of raw materials including oils and oil seeds are provided through import. Camelina sativa L. as an oilseed crop, belongs to Brassicaceae family, has been shown in several experiments that need very little water and resistant to chilling injury than other plant oils, especially canola. This Experiment was conducted at research station of Campus of Agriculture and Natural ...

OBJECTIVE To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice. STUDY DESIGN Randomized controlled trial (RCT). PLACE AND DURATION OF STUDY Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009. METHODOLOGY The study was carried out in 90 male albino mice using aceti...