نتایج جستجو برای: c albicans

تعداد نتایج: 1068200  

2015
Mohd. Asif Sherwani Saba Tufail Aijaz Ahmed Khan Mohammad Owais Joy Sturtevant

BACKGROUND Photodynamic therapy (PDT) has been found to be effective in inhibiting biofilm producing organisms. We investigated the photodynamic effect of gold nanoparticle (GNP) conjugated photosensitizers against Candida albicans biofilm. We also examined the photodynamic efficacy of photosensitizer (PS) conjugated GNPs (GNP-PS) to treat skin and oral C. albicans infection in BALB/c mice. M...

2016
Pim T. van Leeuwen Jasper M. van der Peet Floris J. Bikker Michel A. Hoogenkamp Ana M. Oliveira Paiva Sarantos Kostidis Oleg A. Mayboroda Wiep Klaas Smits Bastiaan P. Krom

The facultative anaerobic polymorphic fungus Candida albicans and the strictly anaerobic Gram-positive bacterium Clostridium difficile are two opportunistic pathogens residing in the human gut. While a few studies have focused on the prevalence of C. albicans in C. difficile-infected patients, the nature of the interactions between these two microbes has not been studied thus far. In the curren...

Journal: :modares journal of medical sciences: pathobiology 2010
elahe mahmoudi hamid reza kalhor mohammad hossein yadegari majid sadeghizadeh zohair mohammad hassan

objective: the secreted aspartic proteinases (sap2) of candida albicans has prominent role on candida adherence, invasion, and pathogenicity. the aim of this study was cloning, expression and characterizing of sap2 enzyme. also in this study for the first time, the expression system p. pasturis was used for expressing the recombinant protein. materials and methods: c. albicans sap2 gene was am...

Journal: :modares journal of medical sciences: pathobiology 2013
hossein rahimi shahla roudbarmohammadi reza kachouei maryam roudbari

objective: approximately three-fourths of women experience an episode of vaginal candidiasis. candida albicans(c. albicans) is the etiological agent in over 80% of cases. c. albicans has numerous virulence factors such as the agglutinin-like sequence (als) genes which code the large glycoprotein family that has a role in the adherence of candida. the present study aims to evaluate expressions ...

2017
M. M. Janus W. Crielaard C. M. C. Volgenant M. H. van der Veen B. W. Brandt B. P. Krom

The yeast Candida albicans is an oral commensal microorganism, occurring in the oral cavity of 50-70% of healthy individuals. Its effect on oral ecology has mostly been studied using dual-species models, which disregards the complex nature of oral biofilms. The aim of this study was to culture C. albicans in a complex model to study its effect on oral biofilms. Biofilms, inoculated using pooled...

Journal: :Microbiology 2001
B Hube J Naglik

Fungal infections of mucosal surfaces are extremely common, debilitating and often recurring diseases, which are frequently caused by the yeast Candida albicans. Furthermore, in the severely immunocompromised host, C. albicans may also cause deepseated or even life-threatening systemic infections. In order to colonize, infect and evade host defence mechanisms, C. albicans possesses a repertoire...

Abbas Ali Amini Ariyo Shahin Jafari Mansour Bayat Marzieh Holakuyee Mehdi Mahdavi Mohammad Hossein Yadegari, Mohsen Abolhassani Zuhair Mohammad Hassan

Background: Candida albicans is one of the most important opportunistic pathogens that suppress immunologic mechanisms of the host. It is speculated that structural and secretory proteins of C. albicans have immunomodulatory effects in cancer. Objective: To evaluate the effects of C. albicans structural and secreted proteins on intratumoral CD4/CD8 ratio as well as the survival rate in BALB/c t...

Journal: :European review for medical and pharmacological sciences 2014
M T Montagna G Lovero E Borghi G Amato S Andreoni L Campion G Lo Cascio G Lombardi F Luzzaro E Manso M Mussap P Pecile S Perin E Tangorra M Tronci R Iatta G Morace

BACKGROUND Candida bloodstream infections (BSI) represent an important problem in Intensive Care Units (ICUs). The epidemiology of candidemia is changing with an increase in the proportion of Candida (C.) non-albicans. OBJECTIVES An Italian 2-year observational survey on ICU was conducted to evaluate the species distribution and possible differences between BSI caused by C. albicans and C. no...

2016
Kearney T W Gunsalus Stephanie N Tornberg-Belanger Nirupa R Matthan Alice H Lichtenstein Carol A Kumamoto

Candida albicans, the most common human fungal pathogen, can cause systemic infections with a mortality rate of ~40%. Infections arise from colonization of the gastrointestinal (GI) tract, where C. albicans is part of the normal microflora. Reducing colonization in at-risk patients using antifungal drugs prevents C. albicans-associated mortalities. C. albicans provides a clinically relevant sys...

2017
Ying Gong Tao Li Cuixiang Yu Shujuan Sun

In recent decades, the incidence of invasive fungal infections has increased notably. Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on human mucosal surfaces, can cause fungal infections, especially in immunocompromised and high-risk surgical patients. In addition, the wide use of antifungal agents has likely contributed to resistance of C. albicans to tradi...

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