We report diffusion coefficients of micron-scale liquid domains in giant unilamellar vesicles of phospholipids and cholesterol. The trajectory of each domain is tracked, and the mean square displacement grows linearly in time, as expected for Brownian motion. We study domain diffusion as a function of composition and temperature and measure how diffusion depends on domain size. We find mechanis...

The immersion precipitation process makes most commercial polymeric membranes, which enjoy widespread use in water filtration and purification. In this work, a ternary Cahn-Hilliard formulation incorporating a Flory-Huggins homogeneous free energy function is used to model both initial diffusion and the liquid-liquid demixing stage of the immersion precipitation process, which determines much o...

Compartmentalization in cells is central to the spatial and temporal control of biochemistry. In addition to membrane-bound organelles, membrane-less compartments form partitions in cells. Increasing evidence suggests that these compartments assemble through liquid-liquid phase separation. However, the spatiotemporal control of their assembly, and how they maintain distinct functional and physi...

The interaction between flowing liquids and solid surfaces underpins many physical phenomena technologies, such as the ability of an airfoil to generate lift mixing for industrial applications. These are often described using Navier-Stokes equations no-slip boundary condition: assumption that liquid immediately adjacent a surface does not move relative surface. Herein, we observe violation cond...

Extraction of Fe(III) from aqueous solution using Trin-butyl Phosphate (TBP) as carrier needs a highly acidic medium (>6N) as it favours formation of chelating complex FeCl3.TBP. Similarly, stripping of Iron(III) from loaded organic solvents requires neutral pH or alkaline medium to dissociate the same complex. It is observed that TBP co-extracts acids along with metal, which causes reversal of...

We present a detailed mechanism for the proton transfer from a protein-bound protonated water cluster to the bulk water directed by protein side chains in the membrane protein bacteriorhodopsin. We use a combined approach of time-resolved Fourier transform infrared spectroscopy, molecular dynamics simulations, and X-ray structure analysis to elucidate the functional role of a hydrogen bond betw...

In this paper we investigate the possibility to detect the hypothesized liquid-liquid critical point of water in supercooled aqueous solutions of salts. Molecular dynamics computer simulations are conducted on bulk TIP4P water and on an aqueous solution of sodium chloride in TIP4P water, with concentration c = 0.67 mol/kg. The liquid-liquid critical point is found both in the bulk and in the so...