Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of drugs. Through this route it is possible to realize mucosal (local effect) and transmucosal (systemic effect) drug administration. In the first case, the aim is to achieve a site-specific release of the drug on the mucosa, whereas the second case involves drug absorption through the mucosal barrie...

A buccal fat pad (BFP) as a flap for reconstruction of defects in the oral cavity has been described for a variety of benign conditions. We describe the indications, advantages, and complications of the BFP flap and report our clinical experience with the flap for intraoral reconstruction after tumor removal. From 2005 to 2008, we analyzed 29 patients in the age range of 32 to 82 years old who ...

UNLABELLED Osteolipoma affecting oral cavity is indeed rare. We hereby report a case of osteolipoma affecting buccal mucosa. A review of literature of osteolipoma of oral cavity, particularly on radiographic/imaging findings was done. Only 16 cases of Osteolipoma of oral cavity are reported in the literature. The radiographic findings of our case, i.e. multiple dense homogenous radio-opaque str...

The electrical activity of the cranial nerves innervating the muscles which contract and dilate the buccal cavity (defined BCcont and BCdil, respectively) was explored in the bullfrog, Rana catesbeiana. The sternohyoid branch of the hypoglossal nerve innervating BCdil showed electrical activity in two consecutive phases: buccal inhalation and lung expiration as well as in the last phase of the ...

Aspirin inhibited glucose absorption from the gastrointestinal tract of the human in viuo (Arvanitakis et al., 1977) and the rat in vitro (Cooke el al., 1979). Glucose was absorbed from the human mouth apparently by a Na+-dependent carrier-mediated process (Manning & Evered, 1976). The aim of the present study was to investigate whether aspirin also inhibited glucose transport across buccal muc...

After the divergence of chondrichthyans and teleostomes, the structure of the feeding apparatus also diverged leading to alterations in the suction mechanism. In this study we investigated the mechanism for suction generation during feeding in white-spotted bamboo sharks, Chiloscyllium plagiosum and compared it with that in teleosts. The internal movement of cranial elements and pressure in the...

Preclinical sheep with the highly scrapie-susceptible VRQ/VRQ PRNP genotype secrete prions from the oral cavity. In order to further understand the significance of orally available prions, buccal swabs were taken from sheep with a range of PRNP genotypes and analyzed by serial protein misfolding cyclic amplification (sPMCA). Prions were detected in buccal swabs from scrapie-exposed sheep of gen...