This article describes the aetiology, epidemiology and clinical significance of incidental non-solid pulmonary nodules. Non-solid nodules are more likely malignant. If malignant, they are mostly due to atypical adenomatous hyperplasia and bronchioloalveolar carcinoma. As these may be negative on positron emission tomography and slow growing, the diagnostic algorithms that are used for solid nod...

Bronchioloalveolar carcinoma (BAC) has a unique clinical and radiological presentation and a different response to systemic treatments compared with conventional lung adenocarcinoma. Although tobacco-related, BAC is found disproportionately in never-smokers, women, and Japanese patients (1). The molecular basis for these predispositions is unknown. The WHO defines BAC as a subtype of adenocarci...

Genetic factors are known to play a role in causing lung cancer. Twin cases of bronchioloalveolar, squamous, and anaplastic bronchogenic carcinoma have been previously reported. We describe mirror-image twins with adenocarcinoma of the lung occurring in mirror-image locations. They shared smoking and an occupational risk, carpentry, in addition to identical genetic backgrounds.