ABSTRACTGuava is one of the plants that can traditionally be used for treatment diseases. Many kinds guava, which Australian guava has characteristics roots, stems, leaves, dark red fruit. This study aims to determine toxicity ethanol extract leaves (Psidium guajava L) using BSLT (Brine Shrimp Lethality Test) method and chemical content L). The was made by ultrasonic 96% solvent. Toxicity tests...

Elaeis guineensis (Arecaceae) is widely used in West African traditional medicine for treating various ailments. An evaluation on the toxicity of extracts of this plant is crucial to support the therapeutic claims. The acute oral toxicity and brine shrimp lethality of a methanolic extract of this plant was tested. Oral administration of crude extract at the highest dose of 5,000 mg/kg resulted ...

PURPOSE The aim of this work was to identify the chemical composition of the essential oils obtained from the flowers and leaves of Elaeagnus angostifolia (Elaeagnaceae) along with evaluate the radical scavenging and general toxicity activities. METHODS A combination of GC-MS and GC-FID were utilized for analyzing the chemical profile of the essential oils extracted by hydro-distillation from...

Diarrhea is one of the most common causes for thousands of deaths every year. Therefore, identification of new source of antidiarrheal drugs becomes one of the most prominent focuses in modern research. Our aim was to investigate the antidiarrheal and cytotoxic activities of methanolic extract of Maranta arundinacea linn. (MEMA) leaves in rats and brine shrimp, respectively. Antidiarrheal effec...

Plants are the natural factories for the synthesis of variety of bioactive compounds. This diverse chemical setup of the plants speaks their important role as biomedicine. These biomolecules are often toxic to both plants and animals. The methanolic extract of Calendula arvensis was screened for its toxic potential against Lemna minor, Artimia salina (Brine shrimps) larvae and some important gr...

The marine ascidian Clavelina cylindrica produces a series of interesting tricyclic quinolizidine and indolizidine alkaloids that show toxicity in a brine shrimp assay.1 Cylindricines A (1), C (2), D (3), E (4), and F (5) differ only in the functionality of the methylene substituent in the fivemembered ring. Interestingly, cylindricines A and B (7) interconvert simply upon standing in solution,...

A new N-acyl taurine (1), together with a new natural product, l-(beta-D-ribofuranosyl)-1,2,4-triazole (4), and two known compounds (2 and 3), were isolated from the sea urchin, Glyptocidaris crenularis. The new N-acyl taurine was elucidated as 2-(5R,15S-dihydroxyeicosanoylamino) ethanesulfonic acid on the basis of spectroscopic (NMR, MS) analyses and the modified Mosher ester method. Compound ...

The aim of the current study was to evaluate Morinda citrifolia (noni) seed extract, a food ingredient, for potential toxicity and antioxidant activity. Nitrates, nitrites, phytic acid, oxalic acid, as well as aflatoxins B1, B2, G1 and G2 were not detected in the extract. The extract was also non-cytoxic (LC50 > 1 mg/mL) in the 24 and 40 h brine shrimp toxicity test. There were no symptoms of t...

ETHNOPHARMACOLOGICAL RELEVANCE Malaria continues to kill over a million people each year and in many populations affected by malaria, conventional drugs are often unaffordable or inaccessible. Historically, plants have been a prominent source of antimalarial drugs. Those plants currently used by indigenous people to treat malaria should be documented and investigated as potential sources of new...