as an important tool for materials characterization in the analytical laboratory. With new developments in laser technology and spectrometer design, handheld Raman spectrometers can now be designed and built for practical everyday use in a vast array of applications [1]. The BRAVO by Bruker takes handheld Raman spectroscopy to a new level, overcoming the limitations of previously available syst...

Ten previously untreated colon carcinomas were tested for chemotherapeutic drug sensitivity in primary monolayer culture. Colon carcinomas were partly digested to groups of epithelial cells which plated with a mean efficiency of 42 ±9% (SE) on a collagen I-bovine serum albumin substrate in serum-free medium, producing patches of tightly adherent epithelial cells. The cultured cells were judged...

Ecoenzymes are natural ingredients formed from the fermentation of fruit and or vegetable residues that have many benefits. One benefits ecoenzymes is they can be used as eco-handsanitizers; which a candidate for handsanitizer those who allergic to alcohol-based handsanitizer. This study aims determine pH, antibacterial, antiviral, antifungal content eco-handsanitizer solution through alkaloid,...

The overall aim of this study was to estimate the contribution of genetic factors to the etiology of hearing loss (HL) in two counties in the Brazilian northeastern region. A cross-sectional study, based on the key informant approach (KI) was conducted in Queimadas and Gado Bravo counties (Paraíba, Northeast Brazil). The sample consisted of 182 patients with HL. Genetic screening of the most fr...

It is a known fact that pH in rodent tumors decline significantly upon heating most likely due to breakdown of the tumor blood circulation. We recently observed that tumor blood vessels become thermotolerant after being heated with a sublethal thermal dose. The purpose of the present study was to reveal whether heating can reduce intratumor pH when the tumor vessels are thermotolerant. When the...

The hypothesis that the naturally occurring analgesic peptide, â-endorphin, is released in the brain in response to pain had never been directly validated. In this study, we applied a brain microdialysis method for monitoring â-endorphin release in vivo, to test this hypothesis in the brains of conscious, freely moving rats. Herein we first show that endogenous â-endorphin can be measured in vi...

A correction was made to Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells. There was a spelling error in one of the authors' surname. The author's name was corrected from: Veronica Rodriquez-Bravo to: Veronica Rodriguez-Bravo.

Introduction Technology now allows up to 96-hour wireless pH-recording in clinical practice; however, no normal values exist for this methodology. This study acquired esophageal pH recordings healthy controls (HC) and compared these against measurements patients with endoscopic evidence of gastroesophageal reflux disease (GORD). Results were used validate the Lyon Consensus Classificat...

BACKGROUND Gastric acid suppressants frequently are used in cats with acid-related gastric disorders. However, it is not known if these drugs effectively increase intragastric pH in cats. OBJECTIVES To examine the effects of PO administered ranitidine and omeprazole on intragastric pH in cats and to compare the efficacy of once-daily versus twice-daily dosage regimens for omeprazole. ANIMAL...