Restoration London saw a wave of publications by physicians advocating that the 'compleat physician' should be one who experimented and produced his own medicines. Only thus, they argued, could the medical hierarchy be restored and medical authority re-established on a defensible basis. This article seeks to explain the context for this unusual approach, and why it failed to attract mainstream ...

BACKGROUND Montelukast (MT) is a leukotriene D4 antagonist. It is an effective and safe medicine for the prophylaxis and treatment of chronic asthma. It is also used to prevent acute exercise-induced bronchoconstriction and as a symptomatic relief of seasonal allergic rhinitis and perennial allergic rhinitis. OBJECTIVE The aim of this study was to evaluate the bioequivalence (BE) of two drug ...

Despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. We highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. We also highlight five key areas for future research: branded drug websi...

Three hundred feedlot steers (320 +/- 2 kg) were assigned to freeze brand, hot-iron brand, and sham branding treatments according to a randomized branding arrangement. Behaviors believed to be indicative of pain (i.e., tail-flicking, kicking, falling, and vocalizing) were recorded during branding. Escape behavior, measured as the amount and duration of force exerted on the headgate and squeeze ...

BACKGROUND In major depressive disorder (MDD), treatment persistence is critical to optimize symptom remission, functional recovery, and health care costs. Desvenlafaxine tends to have fewer drug interactions and better tolerability than other MDD drugs; however, its use has not been assessed in the real world. OBJECTIVE The aim of the present study is to compare medication persistence and co...

despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. we highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. we also highlight five key areas for future research: branded drug websi...