Translationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein present in all eukaryotes. Cellular functions of TCTP include growth promoting, allergic response and responses to various cellular stresses, but the functions in filamentous fungi have not been reported. In this report, we characterized an Aspergillus nidulans TCTP (TcpA) with high similari...

A 52-year-old woman underwent an electrophysiologic prtKedure because of a 30-year history of recurrent episodes of paroxysmal tachycardia. The baseline sinus cycle length wa.s 600 msec and the QRS complexes had a left bundle branch block configuration, with a QRS duration of 120 msec. The atrial-His (AH) and His-ventricular (HV) intervals were 90 and 20 msec, respectively. Programmed atrial st...

The orofacial region is a major focus of chronic neuropathic pain conditions characterized by primary hyperalgesia at the site of injury and secondary hyperalgesia outside the injured zone. We have used a rat model of injury to the maxillary branch (V2) of the trigeminal nerve to produce constant and long-lasting primary hyperalgesia in the V2 territory and secondary hyperalgesia in territories...

The TOR (target of rapamycin) signal transduction pathway is an important mechanism by which cell growth is controlled in all eucaryotic cells. Specifically, TOR signaling adjusts the protein biosynthetic capacity of cells according to nutrient availability. In mammalian cells, one branch of this pathway controls general translational initiation, whereas a separate branch specifically regulates...

The online monitoring of inter-turn short-circuit (ITSC) faults in excitation windings pumped storage units is easily affected by static air-gap eccentricity (SAGE) and armature response, the early fault characteristics cannot be identified effectively. To address these problems, this study proposes a frequency-resolved circulation spectrum (FRCS) diagnosis method for ITSC windings. Firstly, eq...

Peak flow acceleration measured in the common carotid artery was compared with peak flow acceleration measured in the ascending aorta of five chronically instrumented dogs. Electromagnetic flow sensors, myocardial electrocardiographic leads, right atrial catheters, and coronary occluders were implanted through an incision of the chest at the fourth intercostal space and a ventral midline incisi...

Cytochrome P4501B1 (CYP1B1), the major constitutively expressed CYP in the rat mammary gland, is induced by Ah-receptor (AhR) ligands, while CYP1A1 is predominantly expressed only after induction. These CYPs contribute to carcinogenic activation of polycyclic aromatic hydrocarbons (PAHs). AhR, ARNT, and CYP1B1 were only weakly expressed, even after 2,3,7,8-tetrachlorodibenzo-p-dioxin induction,...