conclusions according to our results, silymarin injection caused significant differentiation of mscs to neurons and neuroglia that could be a promising approach for treating a variety of brain injuries. results expression of cd29 and cd90 markers that are characteristic of bmmscs were confirmed by flow cytometry experiments. the data demonstrated that proliferation and number of progenitor cell...

brain injuries that caused by strokes (result of intra partum ischemia) are a frequent cause of prenatal mortality and morbidity with limited therapeutic options. transplanting human mesenchymal stem cells (hmscs) indicates improvement in hypoxic ischemic brain injury (hibd) by secretion growth factor stimulating repair processes (hmscs) known as multi potent cells which isolated from bone marr...

Background: Brainstem hemorrhage was first described by Cheyne in 1812 in a pathological study of patients presenting with lethargy and coma. In 1877 Bode reviewed the findings of 67 patients reported in the literature (1). In the United States, the incidence of closed head injury is estimated to be approximately 200 cases per 100,000 persons per year. The financial burden of head injuries in...

hyperbilirubinemia at neonatal period is one of the major deteriorating factors of the auditory system. if left untreated, it may cause certain cerebral damage. this study aims to evaluate the impact of hyperbilirubinemia on the hearing of neonate. this study was conducted on 35 newborn babies with jaundice (bilirubin more than 20 mg/dl). auditory brainstem response (abr) and transient evoked o...

fourteen patients with bilateral low frequency sensorineural hearing loss were found with disproportionate speech discrimination scores. these patients were submmitted to a comprehensive audiological, electrophysiological, neurological, and radiological battery of investigation. the results pointed to a lesion probably in the central auditory pathway.

one of the main problems following road accidents is brain injury after which death and disability in the most active population occurs. considering the fact that there is no definite clinical treatment for repair of damaged brain tissue, the present study examined the effects of autologous adult neural stem/progenitor cells (ns/pcs) seeded in a nanoscaffold named puramatrix in acute brain inju...