OBJECTIVE To describe feasibility and satisfaction findings from an innovative online family problem-solving intervention for adolescents with traumatic brain injury (TBI). METHODS Nine adolescents who sustained a moderate to severe TBI in the previous 24 months and their families participated in a novel, online, manualized treatment program (Teen Online Problem Solving, TOPS) consisting of 1...

hydatid disease has a worldwide spreading. the most common site of the disease is the liver, lungs, kidney, bones, and brain. splenic hydatid disease has been reported to constitute 2% to 6% of patients with abdominal hydatid disease. because of the rarity of splenic hydatid disease, the probable concomitance of the liver and splenic hydatid cysts should be taken into consideration by clinician...

Amyloid β peptide (Aβ) is the major pathogenic molecule in Alzheimer's disease (AD). BACE1 enzyme essential for generation of Aβ. Deficiency p38α-MAPK neurons increases lysosomal degradation and decreases Aβ deposition brain APP-transgenic mice. However, mechanisms mediating effects are largely unknown. In this study, we used mice cultured observed that deletion specifically decreased phosphory...

the brain parenchyma, and this requires prompt administration of high dose antibiotics and surgical drainage. Brain abscesses frequently arise secondary to hematogenous dissemination, by direct inoculation (trauma or surgery), by contiguous dissemination from an extracranial site or as a complication of meningitis. However, the development of a brain abscess at the site of a prior intracerebral...

objective: transplantation of mesenchymal stem cells (mscs) can promote functional recovery of the brain after hypoxic-ischemic brain damage (hibd). however, the mechanism regulating msc migration to a hypoxic-ischemic lesion is poorly understood. interaction between stromal cell-derived factor-1α (sdf-1α) and its cognate receptor cxc chemokine receptor 4 (cxcr4) is crucial for homing and migra...

Obesity is a Health issue around the world. Obesity is not limited to body weight, generally associated with low grade inflammation and with a cluster of disorders generally referred to as "metabolic syndrome". Regarding obesity and relapse, long-term concentration was set on the hypothalamus. Most recently,obesity- Originated neuroinflammation has been shown to affect other brain str...