Today, neuroscientists are interested in discovering human brain functions through brain networks. In this regard, the evaluation of dynamic changes in functional connectivity of the brain regions by using functional magnetic resonance imaging data has attracted their attention. In this paper, we focus on two model-based approaches, called the exponential weighted moving average model and the d...

One of the most nervous system evolution are memory and learning in humans. Learning is a skill that enhances synaptic activity in the hippocampus of prefrontal cortex. In fact, basic passive learning is communication between the conditioned and Unconditioned stimulation. Passive learning involves three steps: habit, education and remember. According to the results of investigations, the hippoc...

Introduction: The interaction between steroid hormones and neurotransmitters such as GABA has been proved. The regulation of muscimol binding to high-affinity GABAA receptors by estradiol and progesterone has been studied within distinct brain regions using in vitro quantitative autoradiography. There are few studies about the mechanism of the effect of steroid hormones on behaviors such as ...

The variations of glucose 6-phosphate dehydrogenase (G6PD) activity in different brain regions of normal, hypo- and hyperthyroid rats were investigated. Hypo- and hyperthyrodism were experimentaly induced by administration of methimazol and liothyronine, respectively. In normal rats, midbrain had the minimum (70 mU/mg) and cerebral cortex the maximum (349 mU/mg) G6PD activity. Hyperthyrodism in...

objective(s) psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. since studies concerning nerve growth factor (ngf) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on ngf protein levels in various brain regions of rat. materials and methods male wistar rats receiv...

The brain requires O2 and nutrition to keep functioning. It is known that concentration converts the polarity of vessel response near activated neuron in hippocampus. However, it remains unclear whether cortex. We investigated comparison arteriole stimulated neurons cerebral cortex slices between 95% 20% medium. showed diameter blood vessels decreased under when pyramidal cells were increased w...

Objective: The present study investigated possible neuroprotective effects of ethanolic extract of Tiliacora triandra leaf against cerebral ischemic-reperfusion injury in mice. Materials and Methods: Forty male Institute of Cancer Research (ICR) mice were randomly divided into five groups: (1) Sham + 10% Tween 80, (2) bilateral common carotid artery occlu...

After Paul Broca localized the area responsible for producing speech in posterior region of left frontal lobe, John Hurling Jackson provided evidence showing presence different mental functions right and cerebral hemispheres. His theory was confirmed by discovery sensory language Carl Wernicke. Eduard Hitzig Gustav Fritsch identified motor cortex electrical stimulation. David Ferrier also used ...

Aim: Oxidative stress plays a crucial role in the pathophysiology of ischemic stroke. Since water-solublefullerene derivatives act as the potent scavenger of oxygen free radicals in biological systems, we aimedto investigate the possible protective effects of fullerol nanoparticles on brain infarction and edema intransient model of focal cerebral ischemia in rat.Materials & Methods: Experiment ...

Background: Histone deacetylation plays an essential role in transcriptional regulation of cell cycle progression and other evolutionary processes. Several results confirm the importance of the latest found HDAC11 gene to deacetylate histone core in neurons and their supportive cells in developing the vertebrate Central Nervous System (CNS).  Objectives: This study investigates the HDAC11 pote...