A new technique for the treatment of diplopia secondary to cosmetic botulinum toxin A use is described. In this interventional case reports, two consecutive patients who developed diplopia after periocular cosmetic use of botulinum toxin A were treated with intramuscular botulinum toxin A injection into the antagonist extraocular muscle. Diplopia resolved in both patients in less than 1 week wi...

spasticity or increase in muscle tone is one of the problems following stroke. due to this increase in muscle tone, patients are confronted to problems in motor control and difficulties in activities of daily living and complications such as shortness and contracture. the aim of this study is to compare the effects of using splint or botulinum toxin injection on spasticity, range of motion and ...

BACKGROUND Pneumatic dilatation or intrasphincteric botulinum toxin injection provide effective symptom relief for patients with achalasia. Although intrasphincteric botulinum toxin injection is simple and safe, its efficacy may be short-lived. Pneumatic dilatation lasts longer, but esophageal perforation is a risk. We compared treatment costs for pneumatic dilatation and intrasphincteric botul...

BACKGROUND The U.S. Food and Drug Administration has approved four distinct formulations of botulinum toxin (BoNT) serotypes A and B (BoNTA and BoNTB) for medical use. These four products are indicated for many medical applications, but the three BoNTA formulations are the most widely used worldwide and are the only products approved for aesthetic use. The latest approval of a BoNTA with no com...

In this Practice article by Antony Smith and colleagues (BMJ 2013;347:f5170, doi:10.1136/bmj.f5170), the section on use of botulinum toxin A for treating overactive bladder wrongly stated that botulinum toxin type A did not have a UK marketing authorisation for this indication. It should have stated: “At the time of publication (September 2013), most botulinum toxin type A preparations did not ...

our aim was to evaluate the short and long term efficacy of botulinum toxin therapy in iranian patients with achalasia. in a randomized, double blind trial, 20 patients with achalasia, referring to imam khomeini hospital, received either 80 units of botulinum toxin (bt) or placebo (pl) from 1995 to 1998. two weeks later, the response to treatment was assessed on the basis of changes in the symp...

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum and sometimes by strains of Clostridium butyricum and Clostridium baratii. There are three main forms of botulism: foodborne botulism, caused by eating foods containing the botulinum toxin; wound botulism, caused by toxin produced in a wound infected with C. botulinum...

effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats. Abstract Long-term effectiveness and repeated administration of botulinum toxin A are the basis for its use in both neuromuscular disorders and certain painful conditions. Botulinum toxin A has been recently approved for migraine treatment, and its off-label use extends to other craniofacial pain ...