A 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. On physical examination café au lait macular spots were noted on her neck, buttocks and left leg. Bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. Considering the presence of polyostotic fibrous...

a 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. on physical examination café au lait macular spots were noted on her neck, buttocks and left leg. bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. considering the presence of polyostotic fibrous dysplasia, precocious pubert...

Abstract Ligamentum flavum cyst of the lumbar spine has seldom been described. The mechanism formation these cysts remains unknown, but it is thought to be part degenerative process. Although they are clearly visible on imaging studies, frequently wrongly diagnosed as ganglion or synovial cysts. Bone erosion rarely associated with this pathology. Most common symptom back and radicular pain due ...

STUDY DESIGN Cross-sectional study. OBJECTIVE To examine whether bone marrow edema is associated with low back pain in elderly patients with degenerative lumbar scoliosis. SUMMARY OF BACKGROUND DATA The cause of low back pain in degenerative lumbar scoliosis is unclear. METHODS A total of 120 degenerative lumbar scoliosis patients 65 years of age or older were evaluated. Radiography, comp...

Prostate cancer is unique in that bone is often the only clinically detectable site of metastasis. Prostate tumors that have metastasized to bone frequently induce bone pain which can be difficult to fully control as it seems to be driven simultaneously by inflammatory, neuropathic, and tumorigenic mechanisms. As nerve growth factor (NGF) has been shown to modulate inflammatory and some neuropa...

background: osteopoikilosis (opk) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. it is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. we present a case of 34-year-old man suffering from polyarthralgia and low ...

BACKGROUND Since bone marrow receives innervation from A-delta and C-fibers and since an increase in intramedullary pressure in bone marrow may induce acute pain in orthopedic patients during surgery and chronic pain in patients with bone marrow edema, skeletal pain may partly originate from bone marrow. Intraosseous lesions, such as osteomyelitis and bone cancer, are also known to produce cuta...

Several disorders of increased bone turnover and low bone mineral density (BMD) are associated with severe pain that is refractory to treatment with conventional and even opioid analgesics. Because of their ability to effectively improve the underlying pathogenesis of these disorders (i.e., reduce bone resorption and increase BMD), bisphosphonates are considered part of the palliative care of m...

The association of osteomalacia with neurofibromatosis is a very rare entity. Here a 34 year old man, a known case of neurofibromatosis, is reported who presented with bone pain, hypophosphatemia, rena] phosphorus wasting, multiple Looser's pseudofractures, and low bone density. Treatment with high dose calcitriol and phosphate resulted in temporary treatment. Permanent cure was achieved a...