Solitary plasmacytomas are tumors of plasma cell origin that constitute less than 10% of all plasma cell neoplasms. These tumors are categorized as extramedullary plasmacytomas (non-osseous) or solitary plasmacytomas of bone (osseous). Extramedullary plasmacytomas frequently remain localized and usually can be treated effectively with radiation therapy, whereas solitary plasmacytomas of bone fr...

primary breast sarcoma is a rare disease of the breast that comprises a heterogeneous group of malignant mesenchymal neoplasms, including angiosarcoma, liposarcoma, leiomyosarcoma, fibrosarcoma, sarcomas with bone and cartilage, and malignant fibrous histiocytoma. yet the exact incidence of primary breast sarcoma has not been reported, but it approximately accounts for less than 1% of all breas...

BACKGROUND There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified neoplasms such as osteosarcomas and bone metastases. We developed a new therapeutic strategy to target bone metastases and calcified neoplasms using combined polymer-bound angiogenesis inhibitors. Using an advanced "living polymerization" technique, the reversible addition-f...

gressive tumors that account for 4.0-9.5% of all primary bone neoplasms (1, 2). GCT predominates in the long tubular bones, but does, in rare cases, occur in the small bones of the hands and feet. Most GCT cases occur at the sacrum, with only very rare cases occurring during pregnancy (3, 4). We report a case of a GCT involving a metacarpal bone with rapid growth during pregnancy, which was mis...

Primary neoplasms of the patella account for less than 1% of all primary bone tumors of the lower extremity, the most frequent of them being the giant cell tumor of bone, the chondroblastoma, and the aneurysmal bone cyst. Herein, we report the case of a 29-year-old woman with an active giant cell tumor of the patella (GCTP) with its clinical and radiological features and a brief review of the l...

A group of international experts, including haematopathologists, oncologists, and geneticists met on September 2021 in Chicago, IL, USA to update the 2016/17 World Health Organization classification system for haematopoietic tumours. After careful deliberation, introduced new International Consensus Classification (ICC) Myeloid Neoplasms Acute Leukaemias. The was published June 2022 (Arber DA, ...

Aneurysmal bone cysts mostly occur in long bones and spine. It is relatively rare in the maxillofacial region. In this article, we present a 19-year- old woman with the complaint of swelling in the left mandibular premolar tooth. She had got antibiotic therapy after the diagnosis of dental cellulites. On the X-ray study, a well- defined unilocular bony lesion within the preapical premolar tooth...

In spite of the impressive advances in the area of molecular pathology, bone marrow morphology remains the diagnosis cornerstone to identify the various subtypes of myeloid neoplasms. Morphological examination of the bone marrow requires both bone marrow aspirate and bone marrow trephine biopsy. Immunohistochemistry of bone marrow biopsy with markers reactive in paraffin-embedded tissues repres...