نتایج جستجو برای: bone morphogenetic protein 4

تعداد نتایج: 2612758  

Journal: :Clinical Orthopaedics and Related Research® 2009

2016
Alistair E. Cole Simon S. Murray Junhua Xiao

Substantial progress has been made in identifying the extracellular signalling pathways that regulate neural stem and precursor cell biology in the central nervous system (CNS). The bone morphogenetic proteins (BMPs), in particular BMP4, are key players regulating neuronal and glial cell development from neural precursor cells in the embryonic, postnatal, and injured CNS. Here we review recent ...

Journal: :Circulation 2012
Yasuhiro Ogura Noriyuki Ouchi Koji Ohashi Rei Shibata Yoshiyuki Kataoka Takahiro Kambara Tetsutaro Kito Sonomi Maruyama Daisuke Yuasa Kazuhiro Matsuo Takashi Enomoto Yusuke Uemura Megumi Miyabe Masakazu Ishii Takashi Yamamoto Yuuki Shimizu Kenneth Walsh Toyoaki Murohara

BACKGROUND Acute coronary syndrome is a leading cause of death in developed countries. Follistatin-like 1 (FSTL1) is a myocyte-derived secreted protein that is upregulated in the heart in response to ischemic insult. Here, we investigated the therapeutic impact of FSTL1 on acute cardiac injury in small and large preclinical animal models of ischemia/reperfusion and dissected its molecular mecha...

Journal: :Science 2004
Ping Wu Ting-Xin Jiang Sanong Suksaweang Randall Bruce Widelitz Cheng-Ming Chuong

Beak shape is a classic example of evolutionary diversification. Beak development in chicken and duck was used to examine morphological variations among avian species. There is only one proliferative zone in the frontonasal mass of chickens, but two in ducks. These growth zones are associated with bone morphogenetic protein 4 (BMP4) activity. By "tinkering" with BMP4 in beak prominences, the sh...

Journal: :Daehanimsangchoeumpahakoeji 2021

Background/Aim: The purpose of this study was to investigate whether bone morphogenetic protein (BMP)-4 expression differs according the presence calcification in papillary thyroid carcinoma and if BMP-4 are associated with metastasis carcinoma.Methods: We performed using paraffin-embedded tissues 55 patients who underwent thyroidectomy Kosin University Gospel Hospital. Of those cases, 36 were ...

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