Objective: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. In this study, using micronucleus assay, radioprotective effect of OVLE against clastogenic and cytotoxic effect of gamma irr...

Objective- To investigate and compare growth potential as well as aging of mesenchymal stem cells (MSCs) derived from rat bone marrow tissue and adipose tissue (AT) occurred at epicardial and epididymal regions. Design- Experimental study.   Animals- 10 Wistar Rats.   Procedures- Rat MSCs occurred at bone marrow and epicardial and epididymal AT were isolated and culture expanded through sev...

0

experimental and clinical studies have shown that intracoronary transplantation of autologous bone marrow mesenchymal stem cells (bmscs) has resulted in regenerated infarcted myocardium and improved left ventricular (lv) function.the aim of this pilot study was to assess the benefical effectsof intracoronary transplantation of bmsc in patients with oldmyocardial infarction (omi). autologous bms...

background: langerhans' cell histiocytosis (lch) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of langerhans cells. involvement of bone marrow (bm), liver and lung are related to high risk factors and poor survival. the aim of this report is to highlight the clinical and haematological findings of 5 cases of lch with bm infiltration which may help to...

background:  renal transplantation is the best choose in the end stage renal disease (esrd), and acute rejection and graft dysfunction remain major challenges in the worldwide, even with the advent of new immunosuppressive drugs. the novel cell-based anti-rejection treatments have been studied by using different stem cell sources. in this study, transplantation of autologous-bone-marrow-derived...

isolated extramedullary relapse of chronic myelogenous leukemia (cml) after allogeneic stem cell transplant is rare. there is a case report of a child who developed a granulocytic sarcoma of the maxillary and sphenoid sinuses and lumbosacral spinal cord mass 18 months after allogeneic bone marrow transplant for cml. he was presented with per orbital edema and neurological deficit of lower extre...

introduction: this review reports the current results of hematopoietic stem cell transplantation (hsct) in patients who had received transplantation in the hematology-oncology and sct research center, tehran, iran. methods: in iran, from 1991 through 2010, a total of 3170 hematopoietic stem cell transplantation have been carried out. the male/female patient ratio was 1909/1261 with a median age...

objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...