Bone stock deficiency in primary as well as in revision total knee arthroplasty (TKA) represents a difficult problem to surgeon with regard to maintaining proper alignment of the implant components and in establishing a stable bone-implant interface. Different surgical procedures are available in these situations, for instances the use of bone cement, prosthetic augments, custom implant, and wi...

The radiographic and clinical results of 105 patients with symptomatic spinal deformities were categorized retrospectively based on surgical approach and type of bone autograft or allograft used for each patient's fusion surgery into seven different groups and compared with one another. The three bone autograft control groups were posterior autograft only (n = 20), anterior autograft only (n = ...

We carried out a prospective study to determine whether the addition of a recombinant human bone morphogenetic protein (rhBMP-2) to a machined allograft spacer would improve the rate of intervertebral body fusion in the spine. We studied 77 patients who were to undergo an interbody fusion with allograft and instrumentation. The first 36 patients received allograft with adjuvant rhBMP-2 (allogra...

Bulk allograft reconstruction plays an important role in limb-salvage reconstructive surgery but is complicated by nonunion in up to one-third of cases. Because allograft-host healing is mediated via creeping substitution, intimate bone contact is desirable. Intraoperative assessment and optimization of the allograft-host junction site using a conventional transverse osteotomy is challenging an...

Bone loss management is an important consideration in revision total knee arthroplasty (TKA) (Figures 1-3). Large structural allograft use is an option that offers two significant advantages. First, allograft bone is readily available.1 As a graft material, this bone is sterilized and preserved by freezing. Second, allograft bone provides support for the adjacent implant by maintaining its stru...

BACKGROUND Strategies to improve mechanical strength, neovascularization, and the regenerative capacity of allograft include both the addition of skeletal stem cells and the investigation of novel biomaterials to reduce and ultimately obviate the need for allograft altogether. Use of bone cement is a common method of stabilizing implants in conjunction with impacted allograft. Curing cement, ho...

abstract  background: resection of the distal end of the radius is indicated in the treatment  of locally aggressive primary benign and malignant bone tumors. the aim of this study  was to evaluate the technique of osteoarticular allograft reconstruction of the distal radius after wide excision of a giant-cell tumor.  methods: we analyzed 15 patients retrospectively who had reconstruction of th...

The gamma irradiation has been used for end sterilization of allograft bones and its effects with a 25 kGy dosage on the osteoinductive properties of demineralized bone allograft powder was studied. This work carried out using an experimental method in an animal model. In this study the demineralized bone allograft powder which had been sterilized and prepared with gamma irradiation in a 25 kGy...

Introduction: Slipped capital femoral epiphysis (SCFE) is the most common hip disorder affecting adolescent children [1]. The etiology is thought to be multifactorial, related to both biological and biomechanical factors [2]. SCFE occurs when the epiphysis of the proximal femur slips in relation to the metaphysis through the growth plate, causing pain, disability and potential long-term sequell...

Alveolar bone grafting is an integral part of the surgical management of oral clefts. The rationale behind alveolar cleft repair includes maxillary arch stabilization, closure of the oronasal fistula, nasal base support, nasolabial soft tissue reconstruction, and creation of bony support for tooth eruption or dental implant placement. Currently, the graft material of choice is autogenous bone g...