The relationship between dietary intake, circulating hepcidin and iron status in free-living premenopausal women has not been explored. This cross-sectional study aimed to identify dietary determinants of iron stores after accounting for blood loss and to determine whether iron intake predicts iron stores independently of hepcidin in a sample of Australian women. Three hundred thirty eight wome...

introduction: it is generally assumed that 50% of the cases of anemia are due to iron deficiency. the most severe consequence of iron depletion is iron deficiency anemia (ida), and it is still considered the most common nutrition deficiency worldwide. the main risk factors for ida include: inadequate iron intake, impaired absorption or transport, physiologic losses associated with chronological...

Iron homeostasis in the mammalian brain is an important and poorly understood subject. Transferrin-bound iron enters the endothelial cells of the blood-brain barrier from the systemic circulation, and iron subsequently dissociates from transferrin to enter brain parenchyma by an unknown mechanism. In recent years, several iron transporters, including the iron importer DMT1 (Ireg1, MTP, DCT1) an...

Background and Aim: Iron oxide nanoparticles are used in fields related to nanotechnology including ecology, magnetic storage, imaging and medicinal purposes. Iron nanoparticles produce reactive oxygen species (Ros). These materials are able to cross the placenta. The aim of this study was to investigate toxic effect of iron oxide nanoparticles on fetal lung in mice. <br ...

Background: The prevalence of obesity is increasing and many countries are struggling with its high rate and serious complications. As a result of distinct diet in obese children, they may be susceptible to nutritional deficiencies in particular, iron deficiency. This study aimed to examine the relationship between obesity and iron indices. Methods: In this cross-sectional study, 206 element...

BACKGROUND Repeated blood donation alters the iron balance of blood donors. We quantified these effects by analyzing changes in body iron as well as calculating iron absorbed per day for donors enrolled in a prospective study. STUDY DESIGN AND METHODS For 1308 donors who completed a final study visit, we calculated total body iron at the enrollment and final visits and the change in total bod...

BACKGROUND Despite the requirement for increased iron delivery for erythropoiesis during hypoxia, there is very little information on how duodenal iron uptake and its transfer to the blood adapts to this condition. AIMS To assess the effects of 30 days of chronic hypoxia in rats on luminal iron uptake and transfer of the metal to blood, together with gene expression of hepcidin, a proposed ne...

although, iron depletion is a common disorder among athletes, little data exist regarding the effect of gymnastic training on iron status. the objective of this study was to evaluate the effect of gymnastic exercise on body iron status and hematologic profile. the present investigation involved 35 male gymnasts aged from 6 to14 yrs. serum ferritin level, total iron binding capacity (tibc), iron...

trichuriasis is an intestinal parasitic disease which is caused by trichuris trichiura, a soil transmitted helminth. in order to evaluate the iron status of trichuriasis in patients a total of 120 (49 males and 71 females) cases with trichuris trichiura as well as 54 healthy individuals were evaluated. blood samples were analyzed for serum iron, transferrin saturation percent, haemoglobin and o...