Abstract Introduction: There are many studies about the inhibitory effect of the esophageal distention (ED) on gastric motility. Recently, it has been shown that ED decreases the gastric secretions. It is well established that the inhibitory effect of ED is mediated by activation of vago-vagal inhibitory reflex. However, there is not any investigation about the effect of the reflex on the gast...

Arterial drug concentration distribution determines local toxicity. The safety issues dealt with Drug-Eluting Stents (DESs) reveal the needs for investigation about the effective factors contributing to fluctuations in arterial drug uptake. The current study focused on the importance of hypertension as an important and controversial risk factor among researchers on the efficacy of Heparin-Eluti...

  Measurement of blood flow and the effects of different factors on tissue blood flow are important fields of research in physiology and pharmacology. So far, different methods have been innovated, using laser light is the Last one. In this article history, principles and specifications of laser technique along with its advantages and disadvantages ( in comparison with other methods) are revie...

Blood flow is modeled as non-Newtonian micropolar fluid. The non-linear governing equations of continuum and momentum in the cylindrical coordinate are being discretized using a finite difference approach and have been solved iteratively ,through Crank-Nicolson method. The blood velocity distribution, volumetric flow rate and Resistance to blood flow at the stenosis throat are computed for vari...

ranolazine is a new antianginal drug that is postulated to act through blocking of cardiac late sodium channels and improvement in cardiac blood flow. the present study has been carried out to investigate its possible effect on microcirculation of normal and diabetic rats’ cardiac muscle. methods: normal and diabetic rats were anesthetized. the chest was opened and a surface laser doppler flowm...

The aim of this paper is to study the effect of slip velocity and shape of stenosis on non-Newtonian flow of blood through a stenosed arterial segment. Blood is modeled as Bingham-Plastic fluid in a uniform circular tube with a radially non-symmetric stenosis. The problem is investigated by a joint effort of analytical and numerical techniques. The influence of stenosis shape parameter, slip ve...

Background. Although aspirin exerts beneficial antiplatelet activity in patients with coronary artery disease, cyclooxygenase blockade produced by aspirin causes a potentially deleterious effect by interrupting endothelial production of prostacyclin. Collateral vessels that develop in response to coronary occlusion display prominent endothelial cell proliferation and undergo vasoconstriction in...