We present a normal 13-year old female who developed left cerebral infarction following envenomation by the carpet viper (Echis car inat us). We have read of only one other case of cerebral infarction following viper envenomation (Viperi russelli). Possible mechanisms for cerebral infarction in these circumstances are discussed. It is believed that this complication may be more common than is r...

The Bezoar, a dense material found in the stomach of wild goat, is widely used against various diseases including snakebite in traditional medicine among the southeast tribes of Iran. This study was performed to evaluate the Bezoar effect on experimental mice receiving 2% and 10% concentrations of natural crude of Echis carinatus snake venom. Various doses of Bezoar (6, 50, 100 & 200 mg/kg/i....

1. A considerable increase in the plasminogen activator content in the internal jugular venous blood as compared with that in the arterial blood was found in fifty patients. 2. Inhalation of 5 % carbon dioxide in air was associated with increased plasminogen activator content in blood from the internal jugular vein in all the eight patients treated in this way. 3. It is suggested that the human...

The report describes successful management of 10 women in 2nd and 3rd pregnancy trimesters with EchiTab IgG antivenom after carpet viper (Echis ocellatus) envenoming. All women survived but foetal loss in a victim with delayed presentation and a case of mild hypersensitivity reaction were recorded. Excellent outcomes can be achieved in rural and semi-nomadic populations without specialized care...

The plasminogen activator content in the circulating blood has hitherto been thought to derive largely from the endothelium of the veins (Messer, Celander, and Guest, I962; Chakrabarti, Birks, and Fearnley, I963; Warren, I964), though this has been difficult to prove and several other hypotheses have been put forward. Pandolfi and his colleagues (i967), for instance, believe that the plasminoge...

The proliferation of gene data from multiple loci of large multigene families has been greatly facilitated by considerable recent advances in sequence generation. The evolution of such gene families, which often undergo complex histories and different rates of change, combined with increases in sequence data, pose complex problems for traditional phylogenetic analyses, and in particular, those ...

We report the isolation and amino acid sequences of six novel dimeric disintegrins from the venoms of Vipera lebetina obtusa (VLO), V. berus (VB), V. ammodytes (VA), Echis ocellatus (EO) and Echis multisquamatus (EMS). Disintegrins VLO4, VB7, VA6 and EO4 displayed the RGD motif and inhibited the adhesion of K562 cells, expressing the integrin alpha5beta1 to immobilized fibronectin. A second gro...

the measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen. neutralising titration test is a commonly used classical assay for measuring anti-streptokinase antibodies and in this assay the ability of anti-streptokinase antibodies in patients' sera in preventing the lytic ef...