نتایج جستجو برای: blood biomarkers

تعداد نتایج: 771588  

Introduction: Early diagnosis of gastric cancer is the best solution for reversing cancer and curing patients. So far, gastric cancer is diagnosed in late stages due to misinterpretation of symptoms or absence of specific symptoms. Highly sensitive and selective detection methods for biomarkers are needed for early detection. Methods: This paper proposed a new fast screening method, based on t...

Introduction: Fructose is a lipogenic monosaccharide affecting glucose homeostasis and other metabolic biomarkers; however, there is conflicting evidence in this regard. The current systematic review aimed to determine the effects of fructose on metabolic biomarkers in individuals with T2DM using randomized clinical trial studies. Materials and Methods: In this systematic review study, after se...

2013
Saori Kashima Kazuo Inoue Masatoshi Matsumoto Kimihiko Akimoto

BACKGROUND Many markers have been indicated as predictors of type 2 diabetes. However, the question of whether or not non-glycaemic (blood) biomarkers and non-blood biomarkers have a predictive additive utility when combined with glycaemic (blood) biomarkers is unknown. The study aim is to assess this additive utility in a large Japanese population. METHODS We used data from a retrospective c...

Journal: :Journal of Neuroscience Methods 2021

Neurodegenerative diseases are heterogeneous in their cause and clinical presentation making assessment disease monitoring challenging. Because of this, there is an urgent need for objective tools such as fluid biomarkers able to quantitate different aspects the disease. In last decade, technological improvements awareness importance biorepositories led discovery evolving number covering main c...

Journal: :Molecular cancer therapeutics 2009
Windy Berkofsky-Fessler Tri Q Nguyen Paul Delmar Juliette Molnos Charu Kanwal Wanda DePinto James Rosinski Patricia McLoughlin Steve Ritland Mark DeMario Krishna Tobon John F Reidhaar-Olson Ruediger Rueger Holly Hilton

A genomics-based approach to identify pharmacodynamic biomarkers was used for a cyclin-dependent kinase inhibitory drug. R547 is a potent cyclin-dependent kinase inhibitor with a potent antiproliferative effect at pharmacologically relevant doses and is currently in phase I clinical trials. Using preclinical data derived from microarray experiments, we identified pharmacodynamic biomarkers to t...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید