Background: To improve local radicality of surgical treatment for left-sided pancreatic cancer, radical antegrade modular pancreatosplenectomy (RAMPS) was developed. However, no evidences are available regarding the superiority RAMPS to conventional distal pancreatectomy (cDP) in terms long-term outcomes. Objective: assess oncological benefit by comparing outcomes between patients who underwent...

Mg2+ is known to gain access to the NMDA receptor channel from both the extra- and intracellular compartments. Memantine, being an amphiphilic substance, reaches intracellular concentrations of approximately 30 microM, which are much higher than therapeutic extracellular concentrations ( approximately 1 microM). We therefore investigated whether memantine can also block the NMDA receptor channe...

The balanced vehicular traffic model is a macroscopic model for vehicular traffic flow. We use this model to study the traffic dynamics at highway bottlenecks either caused by the restriction of the number of lanes or by on-ramps or off-ramps. The coupling conditions for the Riemann problem of the system are applied in order to treat the interface between different road sections consistently. O...

This paper presents a generalized diversion control model for freeway incident management that is capable of concurrently optimizing the detour rates and arterial signal timings over multiple roadway corridor segments between the freeway and its neighboring arterial. To capture various operational complexities due to the interactions between multiple diversions, this study has extended the mode...

Although the dominant fields in accelerator electromagnets are proportional to the excitation current, precise control of accelerator parameters requires a detailed understanding of the fields in Main Injector[1][2]magnets including contribution from eddy currents, magnet saturation, and hysteresis. Operation for decelerating beam makes such considerations particularly significant. Analysis of ...