BACKGROUND Suction blister epidermal grafting (SBEG) is a simple and effective way of surgical repigmentation in vitiligo. The major problem faced is the time taken for the formation of blisters. Temperature at the suction site is one of the factors affecting the blister formation time. AIMS AND OBJECTIVES To reduce the blister formation time in SBEG by increasing the surface temperature to 4...

Penciclovir is a drug active against herpes simplex viruses located in the epidermis basal layer. The aim of this study was to compare the suction blister technique and microdialysis as methods to measure the penciclovir concentration in the skin after a single dose (250 mg) of its prodrug, famciclovir. Suction blister fluid, microdialysates and plasma were sampled from 11 healthy volunteers fo...

BACKGROUND/PURPOSE Friction blisters, a common injury in sports and military operations, can adversely effect or even halt performance. Given its frequency and hazardous nature, recent research efforts appear limited. Blistering can be treated as a delamination phenomenon; similar issues in materials science have been extensively investigated in theory and experiment. An obstacle in studying bl...

DEAR EDITOR Blister beetle dermatitis is an irritant contact dermatitis, caused when beetles of the genus Paederus are crushed on the skin, releasing the vesicant pederin. It is also known as Dermatitis Linearis or Paedrous Dermatitis. It is characterized by the presence of erythematous and edematous lesions, pain and burning sensation, blisters, pustules and kissing lesions. Though blister bee...

INTRODUCTION Matrix metalloproteinases (MMPs) have various roles in inflammatory states. They seem to be able to modulate endothelial barriers and regulate the activity of chemokines and cytokines. The timely development of the levels during severe sepsis and thereafter have not been investigated. In addition it was of interest to study alterations of MMP-levels in intact skin, as the skin is t...

Blister beetles (Meloidae) are cosmopolitan in distribution except from New Zealand, Antarctica and most Polynesian islands. They act as minor pests for some crops and as major pests for others under certain conditions in several parts of the world. The present work reviews the most important agronomic impacts of various beetle species in different African, Asian, European and American countrie...

The pharmacokinetics of the broad-spectrum penicillin Bay k 4999 were studied in six healthy male volunteers. A 2-g dose was given by the intravenous route. The tissue penetration of the antibiotic was studied by both dermabrasion and blister techniques. A total of 26.4% of the drug was recovered in the urine in 24 h, 79% of this being excreted in the first 2 h. The elimination half-life in ser...