The theory behind an exploding kaleidoscope of protein biomarker research is that reproducible molecular differences that correlate with important medical attributes can be discovered in patient samples and that these molecules can be measured with clinical tests to obtain useful medical information. How could this not be true? Chorionic gonadotropin and cardiac troponins are very good biomarke...

In the past, many have considered the production and use of hydrogen, assuming that it is just another gaseous fuel and can be handled much like natural gas in today’s energy economy. With this study we present an analysis of the energy required to operate an elemental hydrogen economy, with particular reference to road transport. High-grade electricity from renewable or nuclear sources is need...

Although the outlook for a pronounced improvement in the ischaemic limb that cannot be surgically treated remains bleak, cessation of smoking, encouragement of exercise, and the withdrawal of vasoconstricting agents may give some symptomatic relief. There is little evidence that vasodilators or antiplatelet agents have much to offer.

The flood of publications and multiplicity of so-called treatment protocols are an essential problem. Valuable reports mix with pseudo-scientific data, so one can find confirmation or denial of almost every thesis, method or idea. So far, over 200 combinations of timing, operative methods, and sequence of treatment have been described, with a bleak prospect for adoption of common policy and agr...

Abstract Greater Prespa Lake, located on the Balkan Peninsula, is an ancient freshwater lake inhabited by numerous endemic and endangered species represents important part of Europe’s natural heritage. Between 2013 2015, standardized gillnet fishing was conducted for first time ever with aim obtaining large-scale information status fish community in terms relative abundance, biomass, spatial di...