نتایج جستجو برای: bivalent ions

تعداد نتایج: 139779  

Journal: :The Biochemical journal 1996
I G Gazarian L M Lagrimini S J George R N Thorneley

Tobacco peroxidase (36 kDa, pI 3.5) exhibits unique catalytic and spectral properties that are modulated by pH, calcium and magnesium ions. It catalyses the oxidation of veratryl alcohol by hydrogen peroxide over a wide pH range (1.5-5.0) in the presence of these metal ions with a pH optimum of 1.8. This is the only example of a holoperoxidase described so far that is active and comparatively s...

Journal: :Inorganics (Basel) 2023

A new series of some biologically active Cr(III), Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) complexes was synthesized from the reaction Ethyl 6-amino-4-(4-chlorophenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylate (L) with previous biological metals in presence 1,10-phenanthroline monohydrate (Phen). The structures obtained L along their were authenticated by different analytical spectral techniqu...

2018
Lisa K McNeil Robert G K Donald Alexey Gribenko Roger French Nathaniel Lambert Shannon L Harris Thomas R Jones Sheng Li Gary Zlotnick Ulrich Vogel Heike Claus Raquel Abad Julio A Vazquez Ray Borrow Jamie Findlow Muhamed-Kheir Taha Ala-Eddine Deghmane Dominique A Caugant Paula Kriz Martin Musilek Xin Wang Jeni Vuong Leonard W Mayer Michael W Pride Kathrin U Jansen Annaliesa S Anderson

Bivalent rLP2086 (Trumenba), a vaccine for prevention of Neisseria meningitidis serogroup B (NmB) disease, was licensed for use in adolescents and young adults after it was demonstrated that it elicits antibodies that initiate complement-mediated killing of invasive NmB isolates in a serum bactericidal assay with human complement (hSBA). The vaccine consists of two factor H binding proteins (fH...

Journal: :Cell 2012
Junling Jia Xiaobin Zheng Gangqing Hu Kairong Cui Junqi Zhang Anying Zhang Hao Jiang Bingwen Lu John Yates Chengyu Liu Keji Zhao Yixian Zheng

Embryonic stem cell (ESC) pluripotency requires bivalent epigenetic modifications of key developmental genes regulated by various transcription factors and chromatin-modifying enzymes. How these factors coordinate with one another to maintain the bivalent chromatin state so that ESCs can undergo rapid self-renewal while retaining pluripotency is poorly understood. We report that Utf1, a target ...

Journal: :Genetics 2004
Rongling Wu Chang-Xing Ma George Casella

Two major aspects have made the genetic and genomic study of polyploids extremely difficult. First, increased allelic or nonallelic combinations due to multiple alleles result in complex gene actions and interactions for quantitative trait loci (QTL) in polyploids. Second, meiotic configurations in polyploids undergo a complex biological process including either bivalent or multivalent formatio...

2016
Timo Vesikari Jacek Wysocki Johannes Beeslaar Joseph Eiden Qin Jiang Kathrin U. Jansen Thomas R. Jones Shannon L. Harris Robert E. O'Neill Laura J. York John L. Perez

KEY POINTS Concomitant administration of bivalent rLP2086 (Trumenba [Pfizer, Inc] and diphtheria, tetanus, and acellular pertussis and inactivated poliovirus vaccine (DTaP/IPV) was immunologically noninferior to DTaP/IPV and saline and was safe and well tolerated. Bivalent rLP2086 elicited robust and broad bactericidal antibody responses to diverse Neisseria meningitidis serogroup B strains exp...

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