Background Making decision on asthma as an inflammatory disease is done mostly on the airways function and the patient symptoms which most of them are nonspecific and subjective. Also, the children are not able to express their signs and collaboration in examination of the lungs function. Evaluation of serum level inflammatory biomarkers can be useful in assessment of the response to treatment ...

Background and Aim: Oral squamous cell carcinoma (OSCC) accounts for approximately 3% of all cancers worldwide, and if diagnosed early, it has a five-year survival rate of around 85%; however, a late diagnosis may decrease the survival rate to 50%. Aberrant expression of several genes is associated with the hallmarks of OSCC including uncontrolled cell proliferation, poor differentiation, invas...

Background and objectives:  Schizophrenia is a chronic psychiatric disorder, which reduces the patient quality of life. Despite the recommendation for treating this disorder with a minimum dose of medications, antipsychotic polypharmacy has been used experimentally that cause increasing the drug interactions. Aripiprazole has low risk of metabolic has recommended as a first line a treatment fo...

background tracking various biomarkers in serum, gingival crevicular fluid (gcf), and saliva has been introduced as a diagnostic tool for periodontal disease detection. objectives the aim of this study was to compare salivary lactate dehydrogenase (ldh) levels in subjects with periodontal disease and levels in subjects without periodontal disease. conclusions salivary ldh levels can be used as ...

objective(s): silver nanoparticles (ag-nps) are one of the most widely used nanomaterials recently. despite the wide application of nanomaterials, there is limited information concerning their impact on human health and the environment. this study aimed to find the effects of ag-nps (40 nm) on blood serum, liver and kidney tissues of homing pigeons (columbia livia).materials and methods: columb...

A laboratory level microcosm analysis of the impacts of ocean acidification on the environmental stress biomarkers in Portunus pelagicus (Linneaus 1758)exposed to a series of pH regimes expected in the year 2100 (pH 7.5 and 7.0) and leakage from a sub-seabed carbon dioxide storage site (pH 6.5 - 5.5) was carried out. Levels of the antioxidant enzyme catalase, the phase II detoxificatio...

background: consumption of dark chocolate has been often hypothesized to have a role in the prevention of chronic diseases. the objective of this study was to investigate the effects of consumption of dark chocolate (dc) on serum oxidative stress and blood pressure in patients with metabolic syndrome (mets). methods: an 8-week parallel randomized clinical trial involving 114 patients with mets ...

background identification of a normal range for biomarkers, based on pregnancy outcomes (caused by their high or low values) is of special importance in clinical studies. as some pregnancy outcomes can happen in both high and low levels of biomarkers, the receiver-operating characteristic (roc) curve is unsuitable for identifying these levels separately; rather, a statistical method is preferab...