We present a method to produce micropatterns of cells on tissue culture substrates. A network of deep elastomeric microchannels defining the desired pattern is sealed onto the surface of interest, and a protein template is created by injecting sub-milliliter quantities of protein solution into the microchannels. Protein adsorbs only on the areas that were exposed to the microflow. After the cha...

[*] Prof. F. G. Omenetto, P. Domachuk, J. Amsden, J. Bressner Department of Biomedical Engineering and Department of Physics Tufts University, 4 Colby Street Medford, MA 02155 (USA) E-mail: [email protected] S. T. Parker, Prof. J. A. Lewis Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-Champaign 1304 W...

This review of biocompatible lipophilic drug encapsulating and delivery systems entails the basics of colloidal drug delivery with special reference to oil-in-water microemulsion. The behaviour of the biocompatible systems, their formulation and ingredients, physicochemical properties, applications through different routes, advantages and restrictions therein have been presented. In vitro and i...

We report a simple, rapid approach to synthesize water-soluble and biocompatible fluorescent quantum dot (QD) micelles by encapsulation of monodisperse, hydrophobic QDs within surfactant/lipid micelles. Analyses of UV-vis and photo luminescence spectra, along with transmission electron microscopy, indicate that the water-soluble semiconductor QD micelles are monodisperse and retain the optical ...

Biocompatible materials used for the fabrication of dental crowns were studied. Patients were treated with Gold, Porcelain and Zirconia crowns. Dental crowns were selected according to patient’s clinical status and needs. We found that Gold crowns had low patient acceptance because of poor aesthetics and high cost. Gold crowns could not be used opposite to amalgam restorations for the fear of g...

The use of porous blocks is limited, however, because hydroxyapatite has only modest tensile strength and a low fracture toughness, leaving it susceptible to fracture or fragmentation if subjected to mechanical loading. Incorporating hydroxyapatite granules into a biocompatible polymeric matrix produces a more robust material. Judicious selection of the loading level of the HA allows for a high...

Title of Document: SILICON NANOCRYSTALS: BIOCOMPATIBLE FLUORESCENT NANOLABEL Jonghoon Choi, Doctor of Philosophy, 2008 Directed By: Associate Professor, Nam Sun Wang, Department of Chemical and Biomolecular Engineering This study discusses a synthesis, characterization, bioconjugation, and biological responses of fluorescent silicon nanocrystals (SiNCs). First, the efficient method of synthesiz...

Nanotechnology has wide applications in many fields, especially in the biological sciences and medicine. Nanomaterials are applied as coating materials or in treatment and diagnosis. Nanoparticles such as titania, zirconia, silver, diamonds, iron oxides, carbon nanotubes, and biodegradable polymers have been studied in diagnosis and treatment. Many of these nanoparticles may have toxic effects ...

Biocompatibility of electrodes for stimulation are difficult to maintain homeostasis. Noble metal stimulating electrodes which are normally biocompatible on keratinized tissue become very non-biocompatible when they are interfaced with nonkeratinized tissue in an area such as the oral cavity. Composite electrodes have been made biocompatible in the oral cavity even at current densities larger t...

Many observational studies have been conducted on the occurrence of encapsulating peritoneal sclerosis (EPS). However, poorly biocompatible acidic glucose-based dialysis solutions were used in all previous studies. Today, dialysis solutions that are more biocompatible have become widely available. We therefore initiated a new prospective observational study on the occurrence of EPS. The study d...