The objective of this study was to determine whether endogenous sex hormone levels predict cognitive function in older men. Our study design was an exploratory analysis in a population-based cohort in Rancho Bernardo, California. The study participants were 547 community-dwelling men 59-89 yr of age at baseline who were not using testosterone or estrogen therapy. Between 1984 and 1987, sera wer...

Previous reports found that some fluoride-containing dentifrices do not release effective concentrations of fluoride during brushing. Failure to release fluoride can be due to dentifrice matrix components that interfere with the solubilization of the fluoride salts during brushing. A new generation of dentifrices has the capability to precipitate beneficial fluoride salts during tooth brushing....

Epidemiological investigation have suggested that there is a significantly inverse association between circulating 25-hydroxyvitamin D (25(OH)D) and the risk for developing colorectal cancer (CRC) in humans. However, little is known about the role of vitamin D binding protein (VDBP) in colorectal carcinogenesis. Blood samples were collected from 212 CRC patients and 212 controls matched with ag...

Key words: in situ stabilization, bioavailable PB, soil remediation This study was conducted to evaluate the effects of P, Mn oxide, and time on bioavailable Pb in five metal-contaminated soils or mine spoils in the absence or the presence of plants, and to evaluate the effect of those treatments on phytoavailability of Pb, Cd, and Zn. The addition of P or Mn oxide reduced bioavailable Pb compa...

AIMS High androgen levels are presumed by many to explain the male predisposition to coronary artery disease. However, natural androgens inhibit male atherosclerosis(1). Our aim was to determine whether levels of androgens differ between men with and without coronary artery disease. METHODS AND RESULTS Ninety male subjects (60 with positive, and 30 with negative coronary angiograms) were recr...

An in vitro digestion/Caco-2 cell model was used to assess iron bioavailability of twenty elite latematuring tropical maize varieties grown in three diverse agroecologies in West and Central Africa (WCA). Kernel-iron concentration of the varieties, averaged across locations, varied from 19.2 to 24.4 mg kg−1, while mean kernel-zinc concentration ranged between 19.4 and 24.6 mg kg−1. Significant ...

Vitamin D binding protein (DBP) and albumin are the important determinants of circulatory 25(OH)D in adults. Physiological function of vitamin D is particularly regulated by DBPs. Serum parathyroid hormone (PTH) is considered as the biological activity reader of circulating 25(OH)D. We therefore examined the relationships between serum total, free, and bioavailable 25(OH)D versus PTH in apparen...

objective(s): the purpose of the current study was to assess the feasibility of microspheres from biocompatible polymer for oral bioavailability (ba) enhancement of potent sulfonamide- type loop diuretic- furosemide - which used in the treatment of congestive heart failure, caused edema, cirrhosis, renal disease and as an adjunct in acute pulmonary edema. the comparatively poor and inconstant b...

long-term application of fertilizers containing p, especially organic fertilizers, usually increases the water soluble and available p of soil and at the same time may result in p accumulation in soil. organic fertilizers may also increase movement of p in the soil profile that could result in surface and ground water pollution. an experiment was conducted on field plots that received three app...

This review highlights the innovative anti-aging strategies through effective use of calcium supplements. With the advent of pharmacology, modern medical technology and scientific advances in food and nutrition, the longevity of human being significantly improved. However, living long or anti-aging does not make any sense unless people maintain excellent health and quality of life. Thus, mainta...