Nanomaterials, classified as emerging pollutants that are toxic to the environment, known bioaccumulate across different trophic levels in aquatic ecosystem. This study therefore investigates distribution of silver and nanoparticles (AgNPs) environment Skudai River, Johor, Malaysia. Water, sediment, plant, fish samples were collected seasonally along four sites River between May 2018 April 2019...

The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes are crucial in regulating gene expression by controlling chromatin dynamics. Over the last decade, it has become increasingly clear that during neural development in mammals, distinct ontogenetic stage-specific BAF complexes derived from combinatorial assembly of their subunits are formed in neural progenitors and...

The second industrial area located south of Riyadh City – Saudi Arabia was selected for detailed study as pollution of this area with heavy metals has accelerated dramatically during the last decades. The concentrations of eight metals (Cd, Cr, Co, Cu, Fe, Ni, Pb and Zn) in soils and different plant organs of seven native plant species (Calotropis procera , Citrullus colocynthis , Rhazya strict...

Barrier-to-autointegration factor (BAF) is a host cell protein that plays a crucial role in retroviral integration. Preintegration complexes (PICs) stripped of BAF lose their normal integration activity, which can be restored by incubation with purified BAF. BAF bridges double-stranded DNA both intra- and intermolecularly in a non-sequence-specific manner, leading to the formation of a nucleopr...

Barrier to autointegration factor (BAF) binds double-stranded DNA, selected histones, transcription regulators, lamins, and LAP2-emerin-MAN1 (LEM) domain proteins. During early Caenorhabditis elegans embryogenesis, BAF-1 is required to organize chromatin, capture segregated chromosomes within the nascent nuclear envelope, and assemble lamin and LEM domain proteins in reforming nuclei. In this s...

Barrier-to-autointegration factor (BAF) is a conserved metazoan protein that plays a critical role in retrovirus infection. To elucidate its role in uninfected cells, we first examined the localization of BAF in both mortal and immortal or cancerous human cell lines. In mortal cell lines (e.g. TIG-1, WI-38 and IMR-90 cells) BAF localization depended on the age of the cell, localizing primarily ...

Abstract A field experiment was conducted in the lath house of Agricultural Research and Experiment Station College Agriculture governorate Kirkuk-Iraq for period from 1/3/2022 to 1/9/2002, evaluate efficiency N.Oleander L.Album Plenum phytoremediation lead (Pb) contaminated soil by adding Humic acid with three levels (0,5,10) ml..pot −1 directly, design used is R.C.B.D. The results mechanisms ...

Barrier to autointegration factor (BAF) is an essential conserved double-stranded DNA-binding protein in metazoans. BAF binds directly to LEM domain nuclear proteins (e.g. LAP2, Emerin, and MAN1), lamin A, homeodomain transcription factors, and human immunodeficiency virus type 1-encoded proteins. BAF influences higher order chromatin structure and is required to assemble nuclei. BAF also facil...

To date, many anticancer drugs have been developed by directly or indirectly targeting microtubules, which are involved in cell division. Although this approach has yielded many anticancer drugs, these drugs produce undesirable side effects. An alternative strategy is needed, and targeting mitotic exit may be one alternative approach. Localization of phosphorylated barrier-to-autointegration fa...

Barrier to autointegration factor (BAF), which is encoded by the BANF1 gene, binds with high-affinity to double-stranded DNA and LEM domain-containing proteins at the nuclear periphery. A BANF1 mutation has recently been associated with a novel human progeria syndrome, and cells from these patients have aberrant nuclear envelopes. The interactions of BAF with its DNA- and protein-binding partne...