We present a 200 nm in-diameter single-bead sensor for the detection of single, unlabeled DNA molecules in solution using fluorescence resonance energy transfer technology. DNA-bound Alexa 488 and Crimson 625 loaded on commercial beads served as the donor and acceptor, respectively. Binding of the target DNA to the single bead sensor induces G-quadruplex stretching, resulting in a decrease in f...

This paper presents flexible electronics with a bio-compatible material interface for bio-signal monitoring applications. Organic thin-film transistors (TFT) are integrated with the bio-compatible gel interface in a 1.2-μm-thick film substrate. An electrocardiogram (ECG) of a rat is amplified by an organic TFT amplifier circuit that is mounted directly on the surface of the heart. In addition t...

To address the challenges in critical care monitoring, we present a multi-modality bio-signal modeling and analysis modeling framework for real-time human state classification and prediction. The novel bioinformatic framework is developed to solve the human state classification and prediction issues from two aspects: a) achieve 1:1 mapping between the bio-signal and the human state via discrimi...

This paper presents a biosensor-based cattle health monitoring system capable of collecting bio-signals of farm animals in an effective way. For the presented monitoring system. We design an integrated monitoring device consisting of a sensing module to measure bio-signals of cattle such as the heartbeat, the breath rate and the momentum, as well as a Zigbee module designed to transmit the biom...

AMEX, simulate bio-medical measurements. The system simulates a human in which each price pattern represents one bio-medical sensor. Data provided during trading hours from the stock exchanges allowed real-time classification. Classification is based on new machine learning techniques: self-labeling, which allows the application of supervised learning methods on unlabeled time-series and simila...

A narrowband MEMS direction finding sensor has been developed based on the mechanically coupled ears of the Ormia Ochracea fly. The sensor consists of two wings coupled at the middle and attached to a substrate using two legs. The sensor operates at its bending resonance frequency and has cosine directional characteristics similar to that of a pressure gradient microphone. Thus, the directional...