We examined the possible effect of different bilirubin species, including unconjugated (Bu), sugar-conjugated (Bc), and authentic delta bilirubin (Bd) isolated from serum, on the direct enzymatic measurement of uric acid by using the uricase (EC 1.7.3.3) and peroxidase (EC 1.11.1.7) coupled reaction. Bc, isolated from human bile, produced the most interference with uric acid determination. Alth...

We evaluated the Olympus Demand as a cost-saving measure, as a back up to a Technicon SMAC I, and to be the primary instrument for enzyme analysis. In general, it wasfound to be precise, reliable, easy to operate, but with only average turn-around time capabilities. Technically there were several limitations: (1) significant bilirubin interference in the analysis of serum bicarbonate and creati...

Objective(s): Titanium dioxide (TiO2) nanoparticles (NPs) are widely used in commercial food additives and cosmetics worldwide. Uptake of these nanoparticulate into humans by different routes and may exhibit potential side effects, lags behind the rapid development of nanotechnology. Thus, the present study designed to evaluate the toxic effect of mixed rutile and anatase TiO2 NPs on serum bioc...

the aim of this study was to assess the effects of eight weeks of continuous running trainingand four weeks of detraining on lipid peroxidation (mda) and anti-oxidative system response after an acute exercise session. for this purpose, 20 sedentary healthy males were randomly divided into two groups: experimental and control. at the beginning, before and after one acute exercise session, blood ...

background and purpose: the relationship between uric acid and stroke recurrence is ambiguous. some studies have explored this relationship in acute ischemic stroke but had different results. we evaluated the association of admission uric acid level with risk of stroke recurrence in patients with ischemic stroke. methods: we studied ischemic stroke patients presenting to our hospital with magne...

background: increasing serum levels of uric acid (sua) after menopause in women brought up a hypothesis that estrogenic effect may protectively regulate sua. estrogenic effect is a major etiology of uterine fibroids and fibrocystic breast disease. the study aimed to explore sua among patients suffering from these diseases to enhance the hypothesis. methods: overall , 1349 female participants we...

In 1895, Hopkins described the white and yellow wing pigments of Pieridae as ' . . .excretory substances which function in ornament...' (Hopkins, 1895). ^ those days, it was generally recognized that purines, especially uric acid, were excretory products. Hopkins thought that the white substance was uric acid and that the yellow one was a derivative. In 1925 Wigglesworth still believed the wing...