UNLABELLED Several bone-seeking radionuclides (32P, 89Sr, 186Re, and 153Sm) have been used to treat bone pain. The limiting factor in this modality is marrow toxicity. Our hypothesis is that marrow toxicity can be reduced while maintaining therapeutic efficacy using radionuclides that emit short-range beta particles or conversion electrons (CEs). A recent study on 47 patients using the short-ra...

The half-life of the superallowed Fermi $$\beta ^+$$ emitter $$^{14}$$ O was determined to high precision via a direct $$ counting experiment performed at Isotope Separator and Accelerator (ISAC) facility TRIUMF. result, $$T_{1/2}$$ ( O) = 70619.2(76) ms, is consistent with, but more precise than, world average obtained from 11 previous measurements. Combining deduced in present work with most ...

Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...

We demonstrate multi-emitter Si/GexSi1 x npn heterojunction bipolar transistors (HBT’s) which require no base contact for transistor operation. The base current is supplied by the additional emitter contact under reverse bias due to the heavy doping of the emitter-base junction. Large-area HBT test structures exhibit good transistor characteristics, with current gain 400 regardless of whether t...

Lithium 8 is a short lived beta emitter producing a high energy anti-neutrino, which is very suitable for making several measurements of fundamental quantities. It is proposed to produce Lithium 8 with a commercially available 60 MeV cyclotron using protons or alpha particles on a Beryllium 9 target. We have used the GEANT4 program to model these processes, and calculate the anti-neutrino fluxe...

Theranostics is an acronym, which exemplifies the togetherness of diagnostics and therapeutics in the individualized management of disease. The key to personalized medicine in cancer is to determine the molecular phenotypes of neoplasms, so that specific probes can be selected to target the tumor and its microenvironment. Molecular imaging and radionuclide therapy using a particular probe is ba...

A molecular beam epitaxy grown wavelength tunable GaAs p-i homojunction interfacial work-function internal photoemission far-infrared detector is developed. The multilayer (p-ip-i. . . ! detector structures consist of 2, 5, and 10 emitter layers. Experimental results are explained in terms of the number of emitter layers and the doping concentrations of the emitter layer. A detector with 10 mul...