the results of many studies suggested possible relationship between polymorphism at codons 16 and 27 and development of tolerance to beta-2 adrenoceptor agonist responses as well as disease severity in asthmatic patients. this study was designed to evaluate the effect of polymorphism of beta2 adrenoceptors on response to salmeterol and fluticasone (as inhaled seretide). sixty-four patients with...

introduction: hypoparathyroidism (hpt) is an irreversible but preventable disorder caused by an iron overload which can be considered a typical complication in patients with beta-thalassemia major. patients and method: parathyroid function was evaluated in 130 patients in qom, iran, who suffered from beta-thalassemia major. their serum ferritin levels were checked for monitoring of chelation th...

background: members of the eukaryotic hsp90 family function as important molecular chaperones in the assembly, folding and activation of cellular signaling in development. two hsp90 genes, hsp90 alpha and hsp90 beta, have been identified in fish and homeothermic vertebrates but not in poikilothermic vertebrates. in the present study, the expression of hsp90 alpha and hsp90 beta genes in xenopus...

conclusions despite of high resistance of p. aeruginosa, the resistance rate of p. aeruginosa strains isolated from children in the current study was not high. then accurate prescription of antibiotics can decrease the speed of resistance creation. background the first report of pseudomonas aeruginosa (p. aeruginosa) carbapenem resistant strains, and especially the metallo-beta-lactam (mbl) pro...

abstract background the aim of the present study was to determine the endocrine dysfunction in patients with major thalassemia, who receive hyper transfusion. materials and methods this cross sectional study was performed during one year, which included 65 major thalassemia patients (31 females and 34 males), aged between 14 month to 27 years old (median 10,3). growth assessment was measured by...

background recent studies regarding the effect of hydroxyurea (hu) in thalassemia have revealed favorable effects on the reduction of ineffective erythropoiesis. objectives the aim of the current study was to evaluate whether or not hu can have an effect on the gallstone formation rate in patients with beta-thalassemia intermedia (bti). patients and methods in this case control cross-sectional ...

conclusions single dose therapy of mtx has sufficient power and efficacy in the treatment of ectopic pregnancy, however in patients with higher serum level of β-hcg, the successful treatment increases by using double dose method. using double dose also could decrease the necessity of operation, re-administration of mtx, and duration of hospitalization. results results showed that the rate of su...

conclusions regarding the importance of metallo-beta-lactamase (mbl) produced by pseudomonas spp. isolated from hospitals, quick identification of clinical samples should be considered as an important and basic step to treat and control infections caused by pseudomonas spp. results strains with mic > 4 µg/ml were investigated by phenotypic and genotypic methods. in the current study the rate of...

begin{abstract} the relations between the spectrum of the matrix $q+r$ and the spectra of the matrices $(gamma + delta)q+(alpha + beta)r-qr-rq$, $qr-rq$, $alpha beta r-qrq$, $alpha rqr-(qr)^{2}$, and $beta r-qr$ have been given on condition that the matrix $q+r$ is diagonalizable, where $q$, $r$ are ${alpha, beta}$-quadratic matrix and ${gamma, delta}$-quadratic matrix, respectively, of order $...