Serrated adenomas (SAs) are part of the distinct serrated polyp pathway of colorectal carcinogenesis characterized by microsatellite instability and deficiency in DNA mismatch repair. Sessile SA is a recently recognized lesion that typically presents as a large sessile polyp, but lacks the conventional dysplasia. It is more frequently found on the right side than on the left side of the colon, ...

Spontaneously mutated multiple oncogenes and/or tumor suppressor genes in colon epithelial cell and its progeny, may cause proliferation out of control and create benign colon neoplasm (colon polyp). If additional mutations involve genes responsible for cell adhesion and movement, aberrant epithelial cells may become malignant (colon cancer) and invade surrounding and remote tissues, creating s...

Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances both in the gastrointestinal tract and in the epidermis. The pathologic finding of the polyp is usually a hamartomatous polyp of the juvenile type; however, the possibility of serrated adenoma associated malignant neoplasm was reported in some Japanese cases. Up till now in South Ko...

Gastric protruding lesions are frequently encountered by health screening esophagogastroduodenoscopy. They can be classified into epithelial lesion and subepithelial lesion. Epithelial gastric lesions are generally divided into benign and malignant. Benign lesions include some types of polyps, i.e., hyperplastic polyp, fundic gland polyp, and gastric adenoma. Malignant lesions include carcinoid...

The stomach is far less rich in polyps than is the colon. As a result, we know much less about gastric polyps than colonic polyps, and the literature tends to be much more recent and sparser. About 5 to 10% of biopsies of endoscopic gastric polyps are normal mucosa. The reasons for this include the biopsy forceps missing the lesion, an intramural lesion that is not available to endoscopic biops...

Colorectal cancer is one of the main causes incident cases and deaths worldwide. Undetected colon polyps, be them benign or malignant, lead to late diagnosis colorectal cancer. Computer aided devices have helped decrease polyp miss rate. The application deep learning algorithms techniques has escalated during this last decade. Many scientific studies are published detect, localize, classify pol...

lon polypectomy. A colonoscopic examination had been carried out in another hospital several days earlier due to hematochezia and a polyp had been found in the sigmoid colon. The 1.5-cm, pedunculated polyp (●" Fig. 1) had a slight bulge in the stalk, and there was a mucosal bridge at the attachment to the intestinal wall, mimicking a submucosal tumor. The polyp was resected at the midportion of...

Colon cancers arise from benign neoplasms and evolve into adenocarcinomas through a stepwise histological progression sequence, proceeding from either adenomas or hyperplastic polyps/serrated adenomas. Genetic alterations have been associated with specific steps in this polyp-adenocarcinoma sequence and are believed to drive the histological progression of colon cancer. Recently, epigenetic alt...

backgrounds and objectives: today we are witnessed a growing number of minimally invasive surgical techniques for different diseases. laparoscopic colon surgery as a minimally invasive surgery is currently growing in treatment of malignancies after proving his place in the treatment of benign diseases. we compare in this study results of laparoscopic colorectal surgery with open surgery. method...

The author investigated histopathology of 615 consecutive duodenal specimens in our pathology laboratory. Computer search of the duodenal lesions was performed. Review of histological slides was done, when appropriate. The duodenal specimens were composed of 567 benign lesions and 48 malignant lesions. The 567 benign lesions were composed of chronic non-specific duodenitis in 334 cases (60.0%),...