BACKGROUND Insulin glargine provides effective glycemic control when administered at bedtime in adults. OBJECTIVE This study aims to investigate whether insulin glargine is equally effective if administered in the morning or at bedtime in combination with preprandial anologue insulin. METHODS Twenty-eight patients that have been treated with an intensified insulin regimen for at least one y...

Many older adults (seniors) experience problems with getting enough sleep. Because of the link between sleep and circadian rhythms, changes in bedtime lead to changes in the amount of sleep obtained. Although primarily determined genetically, chronotype changes with advancing age towards a more morning-type (M-type) orientation. In a 2006 study, we have found a linear relationship, by which the...

Recent interest in sedentary behavior and technological advances expanded use of watch-size accelerometers for continuous monitoring of physical activity (PA) over extended periods (e.g., 24 h/day for 1 week) in studies conducted in natural living environment. This approach necessitates the development of new methods separating bedtime rest and activity periods from the accelerometer recordings...

OBJECTIVE To use a portable continuous glucose monitoring system (CGMS) to evaluate how well the customary intermittent self-monitoring of blood glucose (SMBG) correlates with integrated values during the surrounding time periods in ambulatory patients with type 1 diabetes. RESEARCH DESIGN AND METHODS In the study, 18 young patients with type 1 diabetes were monitored with CGMS for up to 72 h...

OBJECTIVE To investigate the relationship between specific television-viewing habits and both sleep habits and sleep disturbances in school children. METHODS The parents of 495 children in grades kindergarten through fourth grade in three public elementary schools completed two retrospective survey questionnaires, one assessing their children's sleep behaviors and the other examining televisi...

OBJECTIVES Causal links between disrupted sleep and behavioral problems in nonclinical populations are far from clear. Research questions were as follows: Are bedtime schedules associated with behavioral difficulties? Do effects of bedtime schedules on behavior build up over early childhood? Are changes in bedtime schedules linked to changes in behavior? METHODS Data from 10,230 7-year-olds f...

STUDY OBJECTIVE to determine whether melatonin will improve quality of sleep in healthy older people with age-related sleep maintenance problems. DESIGN a double blind randomised placebo controlled crossover trial in healthy older volunteers. SETTING a largely urban population, Auckland, New Zealand. PARTICIPANTS participants were part of the larger Possible Role of Melatonin in Sleep of ...