Nanotechnology and, specifically, nanomedicine has been touted as the next breakthrough technology for medical sciences. Although there are large advances being seen in the preclinical phases of development, there is still a paucity of viable and effective nanomedicine technologies in the clinical setting. We attempt to provide some suggestions as to the stumbling blocks of meaningful translati...

Introduction: The Co-word analysis has the ability to identify the intellectual structure of knowledge ‎in a research domain and reveal its subsurface research aspects.‎ Objective: This study examines the intellectual structure of knowledge in the field of nanomedicine ‎during the period of 2009 to 2018 by using Co-word analysis.‎ Materials and Methods: This paper develops a sciento...

cell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. however, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. nanomedicine...

The growing research interest in nanomedicine for the treatment of cancer and inflammatory-related pathologies is yielding encouraging results. Unfortunately, enthusiasm is tempered by the limited specificity of the enhanced permeability and retention effect. Factors such as lack of cellular specificity, low vascular density, and early release of active agents prior to reaching their target con...

The size of a nanomedicine strongly correlates with its biodistribution, tissue penetration, and cell uptake. However, there is limited understanding how the size of nanomedicine impacts the overall antitumor efficacy. We designed and synthesized camptothecin-silica nanoconjugates (Cpt-NCs) with monodisperse particle sizes of 50 and 200 nm, two representative sizes commonly used in drug deliver...

Nanomedicine for diagnosis and treatment of disease, as a discipline has been around for several years, with the first nanotherapeutic product being approved in 1995. Worldwide its importance was recognized with the setting up of several nanomedicine centres in 2004-2006. Many of these centres were set up to accelerate the speed of translation of the research. In this article we review, with a ...