Intravesical instillation of Bacillus Calmette-Guerin (BCG) hasbecome an established adjuvant treatment for superficial bladdercarcinoma. This treatment is associated with a relatively high rateof side effects which are mostly reversible spontaneously or canbe treated symptomatically. Serious systemic side effects are lessfrequent. One of rare complications is gran...

Ecological studies are one of the most common study designs used to establish association between certain factors and disease development. However, they have limitations mainly on how measure variables, so their results must be verified in with greater validity. Therefore, that links possible relationship higher mortality from COVID-19 non-vaccination by bacillus Calmette-Guerin (BCG) was recen...

We report a case of bilateral Eales’ disease managed with intravitreal bevacizumab. A 32-year-old woman history bacillus Calmette-Guerin vaccine, administered when she was 10 years old, presented five-day scotoma in the temporal field her right eye. dilated fundus exam and fluorescein angiography showed retinal peripheral capillary non-perfusion, neovascularization eye, deep intraretinal hemorr...

Background: The Bacillus Calmette-Guerin (BCG) vaccine has long been used for the prevention of tuberculosis (TB) around world. BCG is also as an immunotherapy agent treatment non-muscle invasive urinary bladder cancer. This scoping literature review and preliminary data analysis aims to summarize correlating infantile vaccination with incidence future Methods: Studies were identified by a form...

Tuberculosis (TB), known as the White Plague is of great significance to humanity for magnitude morbidity and mortality it has generated over centuries from very start human civilization. In this Review, we will describe history prevention (vaccination management TB infection), diagnosis, treatment, pulmonary rehabilitation post-treatment sequelae. The article leads reader through main discover...

The lethality of Sarcoma 180 (S-180) for mice has been well documented. However, it was reported recently that definite protection following implantation resulted if the animals were previously infected with Bacillus Calmette-Guerin (11). This effect has been attributed to the enhancement of the activity of the reticuloendothelial system (R.E.S.) (1, ~) and the subsequent increase in natural re...

Tuberculosis is a serious infection disease which causes more than two million deaths annually. The TB pandemic has continued despite widespread use of the only available licensed TB vaccine--Bacillus Calmette-Guerin (BCG). Additionally, the increasing incidences of multidrug resistant strains and coinfection with HIV mean that tuberculosis constitutes a growing global threat. Thus, improvement...

BCG (Bacillus Calmette Guerin) being a live attenuated vaccine may cause disseminated disease (BCGiosis) in patients with impaired immunity. Patients with severe combined immunodeficiency (SCID) having defect in both cellular and humoral immunity are predisposed to a host of live vaccine related complications, especially BCG. We report an infant presenting persistent fever, weight loss, anemia,...

PURPOSE In the present study booster efficacies of Ag85 B, Bacillus Calmette-Guerin (BCG), and Ag85B peptides were evaluated using prime boost regimes in BALB/c mice. MATERIALS AND METHODS Mice were primed with BCG vaccine and subsequently boosted with Ag85B, BCG and cocktail of Ag85B peptides. RESULTS Based on analysis of immune response it was observed mice boosted with Ag85B peptides sho...

Mycobacterium tuberculosis infects one third of the world's population. Due to variable efficacy of the Bacille Calmette Guerin (BCG) vaccine, development of novel TB vaccines remains a priority. Here, we demonstrate the protective efficacy of a novel multivalent DNA vaccine, which contains 15 synthetic antigens targeting the Mtb ESX secretion system.