The present study investigates the effect of commonly used negative and positive allosteric modulators of the calcium-sensing receptor (CaSR) on vascular reactivity. In wire myography studies, increasing [Ca2+]o from 1mM to 6mM induced concentration-dependent relaxations of methoxamine-induced pre-contracted rabbit mesenteric arteries, with 6mM [Ca2+]o producing almost complete relaxation. [Ca2...

Abstract Different metal matrix ceramic composite plates were manufactured using different diameter balls. The ballistic resistance of these investigated by firing 12.7mm, 25mm armor-piercing incendiary (API), and 200 standard explosively formed projectile(EFP). tests results showed that balls with higher mechanical properties performed better resistance, in the meantime, there was a correlatio...

Purpose: To investigate the effect of newly designed photochromic Senofilcon-A lens(PCL) on optical aberrations eye (total (TA) and high-order-aberrations (HOA)) under ambient illumination conditions.
 Methods: In this retrospective study, 40 eyes 20 volunteers were fitted with a non-photochromic contact lens right eye, PCL left eye. Subjects evaluated in terms best-corrected visual-acuity...

Two Niand Cu-free bulk metallic glasses (BMGs) of Zr65Pd17:5Fe10Al7:5 and Zr65Pd12:5Ag5Fe10Al7:5, with a critical casting diameter of 6mm and a compressive strength above 1500MPa, were developed. While the Zr65Pd17:5Fe10Al7:5 alloy showed little plastic strain before fracture, the Zr65Pd12:5Ag5Fe10Al7:5 alloy exhibited much larger plasticity by the relatively stable, intermittent propagation of...

Objective: CT colonography (CTC) is recommended after positive fecal occult blood testing (FOBt) when colonoscopy is incomplete or infeasible. We aimed to estimate the sensitivity and specificity of CTC for colorectal cancer and adenomatous polyps following positive FOBt via systematic review. Methods: The MEDLINE, EMBASE, AMED and Cochrane Library databases were searched for CTC studies report...

The objective of this study was to gain insight into the mechanisms underlying heating-induced tenderness in muscle food products by comparing tenderness changes in chicken breast (Pectoralis major) and salmon (Oncorhynchus gorbuscha) during high-temperature treatment. Relationships among changes in chicken breast and pink salmon muscle were investigated for tenderness, cook loss, area shrinkag...

Objectives The extent of para-aortic lymph nodes (PANs) metastasis is equivalent to distant metastases in patients with biliary carcinoma. Accurate preoperative assessment of PANs metastasis has a crucial impact on surgical indication. In this retrospective study, we evaluated whether computed tomography (CT) scans were useful for diagnosing PANs metastases and excluding patients with PANs meta...

Abstract The following paper presents the development of a novel magnet system for use in 1 kg Planck balance. For this purpose, several preliminary theoretical and experimental investigations were carried out an optimized prototype magnetic was modeled, designed built based on results. Initial measurements showed that with outer diameter 104mm height 50mm achieved constant average value 85 . 2...