In the title mol-ecule, C(5)H(7)N(3)S, the thia-zine ring shows a conformation close to a half-boat. The Cremer & Pople puckering parameters of the thia-zine ring are q2 = 0.4645 (2) Å, θ = 132.4 (3) and ϕ = 285.52 (2)°. The packing is stabilized by inter-molecular N-H⋯N and C-H⋯S inter-actions.

In the title compound, C(15)H(19)Br(3)N(2)O(4)S, the thia-zine ring adopts a distorted half-chair conformation. The enolic H atom is involved in an intra-molecular O-H⋯O hydrogen bond, forming a six-membered ring. In the crystal, the mol-ecules are linked into a three-dimensional network through inter-molecular N-H⋯O, N-H⋯Br and O-H⋯Br hydrogen bonds.

In the title compound, C(14)H(11)Cl(2)N(3)S, the thia-zole ring is in an envelope conformation with the -CH(2)- group bonded to the S atom forming the flap. The crystal structure is stabilized by weak inter-molecular C-H⋯Cl and C-H⋯N hydrogen bonds.

In the title compound, C(15)H(12)BrNO(2)S, the dihedral angle between the two aromatic rings is 87.81 (8)°. The five-membered thia-zolidine ring has an envelope conformation, with the S atom displaced by 0.4545 (7) Å from the mean plane of the other four ring atoms. The crystal structure exhibits O-H⋯O, C-H⋯O, C-H⋯Br and C-H⋯ π inter-actions.

The title compound, C(16)H(13)ClFNOS, possesses potent anti-bacterial activity. The overall mol-ecular conformation is described by the dihedral angles of 43.0 (1)° between the 3-chloro-4-methyl-benzene and thia-zolidinone rings, and 88.8 (5)° between the thia-zolidinone and 4-fluoro-benzene rings. The 3-chloro-4-methyl-benzene ring is disordered over two positions with occupancy factors approx...

In the title mol-ecule, C(9)H(8)N(4)O(2)S, the dihedral angle between the thia-diazole and benzene rings is 73.92 (8)° and the thia-diazole group S atom is orientated towards the benzene ring, the central S-C-C-C torsion angle being 45.44 (18)°. In the crystal, supra-molecular tapes mediated by N-H⋯N hydrogen bonds and comprising alternating eight-membered {⋯HNCN}(2) and 10-membered {⋯HNH⋯NN}(2...

The title mol-ecule, C(18)H(12)N(4)S(3), consists of three essentially planar fragments, viz. two methyl-substituted benzonitrile rings and a substituted thia-diazole ring. The dihedral angles between the substituted benzonitrile rings and the central thia-diazole ring are 28.29 (10) and 78.83 (6)°, and the dihedral angle between the two benzonitrile rings is 72.89 (7)°.

In the title compound, C(16)H(11)F(4)N(3)S, the dihedral angles between the thia-diazole ring and the difluorobenzyl rings are 81.95 (7) and 81.96 (7)°, whereas the dihedral angle between the difluorobenzyl rings is 11.41 (7)°. In the crystal structure, C-H⋯N and C-H⋯F inter-actions link the mol-ecules into two-dimensional arrays parallel to the bc plane.

In the title molecule, C(26)H(24)N(4)O(2)S, the dihedral angle between the isoxazole ring and the adjoining benzene ring is 21.4 (5)°, and between the isoxazole ring and the thia-zole ring is 14.3 (4)°. The piperidine ring is in a chair conformation. In the crystal structure, mol-ecules are linked by inter-molecular N-H⋯O and weak C-H⋯O hydrogen bonds into one-dimensional chains along [001].

In the structure of the title compound, C(18)H(15)ClN(4)O(4)S, the dihedral angle between the two benzene rings is 1.4 (3)°. The angle between the phenyl ring and thia-diazole ring is 5.8 (4)°. The conformations of the N-H and C=O bonds are anti with respect to each other. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯N, N-H⋯O and O-H⋯O hydrogen bonds, forming a three-d...