Rapidly evolving implantation and alveolar ridge reconstruction techniques created a new area in modern dentistry where tooth loss is no longer a problem. Endless variations of implant's length, diameter, surface, and design along with autogenous, alogenous, aloplastic, or xenogenous bone substitutes made it possible to recreate physiological occlusion, esthetic and masticatory function. Howeve...

BACKGROUND To avoid a pneumonectomy and preserve the lung parenchyma, a bronchovascular double-sleeve plasty including an extended sleeve lobectomy is a good choice for locally advanced lung cancer. CASE PRESENTATION We describe a case with lung adenocarcinoma enrolled in our new protocol for ex situ auto-lung transplantation following an en bloc pneumonectomy and back table procedure for cen...

objective: we evaluated structural and functional changes of fresh and frozen-thawed adult mouse spermatogonial stem cells following auto-transplantation into gamma-irradiated testes. materials and methods: in this experimental research, the right testes from adult mice (n=25) were collected, then sertoli and spermatogonial cells were isolated using two-step enzymatic digestion, lectin immobili...

A llogeneic and autologous haematopoietic stem cell (HSC) transplantation are now both established as principal forms of treatment for patients with acute or chronic leukaemia, aplastic anaemia and various immunodeficiency syndromes, as well as various nonhaematological malignancies and auto-immune disorders [1–3]. However, major limitations to the successful use of HSC transplantation include ...

Objectives To analyze the outcomes of patients who received autologous stem cell transplantation (auto-SCT), matched sibling donor (MSD-SCT) and haploidentical (haplo-SCT) provide basis for choice method in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).Methods We retrospectively investigated 119 adult with Ph+ ALL our center. The overall survival (OS) rate, leukemia-fr...

odgkin’s lymphoma (HL) is a B-cell malignancy that affects 000 new patients annually in the USA, representing approxmately 11% of all lymphomas.1 In the last decades, randomzed clinical trials conducted by cooperative groups in North merica and Europe have identified treatment schedules that rovide higher efficacy and lower toxicity with current treatent being expected to cure over 80% of patie...

Autologous hematopoietic stem cell transplantation (auto-HSCT) is presently the only disease-modifying strategy for treatment of systemic sclerosis (SSs) that has Level A evidence, effectiveness which been proven in three controlled clinical trials: ASSIST, ASTIS, and SCOT. Despite positive results obtained with use this option, issues related to its tolerability safety remain unresolved. The c...

Introduction: There is little iterature data regarding neutropenic enterocolitis (NE) development after autologous hematopoietic cell transplantation (auto-HCT) in non-Hodgkin lymphoma (NHL) patients. The aim of this study was to determine the incidence, risk factors, and clinical outcome NE auto-HCT NHL patients with respect impact multidrug-resistant Gram-negative bacteria (MDRG) vancomycin-r...

INTRODUCTION Posttransplant lymphoproliferative disorder (PTLD) is a serious complication following solid organ or hematopoietic stem cell transplantation (HSCT). Although extranodal involvement of PTLD is common, its isolated involvement in the central nervous system (CNS) is extremely rare. To date, primary CNS-PTLD has been reported in 13 patients who underwent allogeneic HSCT, but no cases ...