نتایج جستجو برای: auto inhibition
تعداد نتایج: 354924 فیلتر نتایج به سال:
Submitted for the CAL10 Meeting of The American Physical Society Casein Kinase 2 Reverses Tail-Independent Inhibition of Kinesin11 JING XU, ZHANYONG SHU, PREETHA ANAND, BABU REDDY, SILVIA CERMELLI, THOMAS WHISENANT, UC Irvine, STEPHEN KING, University of Missouri-Kansas City, LEE BARDWELL, LAN HUANG, STEVEN GROSS, UC Irvine — Kinesin-1 is a plus-end microtubule-based molecular motor, and defect...
Service-oriented architectures (SOA) and, in particular, Web Services designs are widely adopted for the development of interoperable systems. In a dynamic scenario, a composed service may exploit component services in order to complete its task; composed services are variously distributed, and offered by different providers in different security domains and under different load conditions. So,...
Rheumatoid arthritis (RA) is the most common form of chronic inflammatory rheumatism. Identifying auto-antigens targeted by RA auto-antibodies is of major interest. Alpha-enolase (ENO1) is considered to be a pivotal auto-antigen in early RA but its pathophysiologic role remains unknown. The main objective of this study was to investigate the in vitro effects of soluble ENO1 on peripheral blood ...
STIM1 (stromal interaction molecule 1) is one of the key elements that mediate store-operated Ca²⁺ entry via CRAC (Ca²⁺- release-activated Ca²⁺) channels in immune and non-excitable cells. Under physiological conditions, the intramolecular auto-inhibitions in STIM1 C- and STIM1 N-termini play essential roles in keeping STIM1 in an inactive state. However, the auto-inhibitory mechanism of the ST...
Sera taken from AKR/J mice 7 d after the intravenous injection of 2,4,6-trinitrophenyl-lys-Ficoll (TNP-F) caused a specific inhibition of anti- trinitrophenol (TNP) plaque-forming cells (PFC) in vitro. This inhibition was reversed by the incorporation of 10(-8)-10(-7) M 2,4,6-trinitrophenyl- epsilon-amino-n-caproic acid (TNP-EACA) into the agar during the PFC assay. The factor responsible for t...
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