The direct enantioselective construction of axially chiral 3-arylindole frameworks via nucleophilic addition 2-substituted indoles to iminoquinones has been achieved with high efficiencies under mild phosphoric acid (CPA) catalytic conditions. utility this method was demonstrated in successful scale-up syntheses without compromising the product yields and enantioselectivities. oxidation product...

Chiral polychlorinated biphenyls (PCBs) were measured in an arctic marine food web from the Northwater Polynya (NOW) in the Canadian Arctic to examine potential biotransformation of chiral PCB atropisomers. Organisms under investigation included pelagic zooplankton, Arctic cod (Boreogadus saida), seabirds, and ringed seals (Phoca hispida). Previous studies using achiral methods (e.g., biomagnif...

Abstract Phenanthroline ligands bearing two biphenyl ( L1 ) or tetraarylbenzene L2 substituents have been synthetized and used to prepare bis‐phenanthroline copper(I) complexes. Steric constraints are limited in the case of biphenyl‐substituted ligand [Cu( 2 ](BF 4 has obtained by reaction with [Cu(CH 3 CN) ). In contrast, large enough totally prevent formation corresponding homoleptic complex....

Metolachlor exists in multiple, different stable conformations in solution. Assignment of the NMR frequencies to chemical structure is a prerequisite to understanding the behavior of individual conformations. (1)H NMR experiments of metolachlor in different chemical environments identified the labile sites of metolachlor and environments that influence conformational/configurational changes. Wi...

The existence of biphenyl-type atropisomerism in porphyrins has been known for more than twenty-five years. Over the last two decades, different examples of this type of stereoisomerism have been reported in the literature with regard to the use of synthetic metalloporphyrin complexes as models of heme-containing enzymes. In this article, we present a clear 1H NMR study to illustrate the concep...

The front cover picture illustrates the palladium-catalyzed chirality transfer from peripheral stereogenic carbon center to axial starting 8H-indenothiophen-8-ols. process is different traditional point-to-axial aromatization reaction of a non-aromatic intermediate, in which new created chiral axis usually directly attach centers. This provides an easy way access highly functionalized 3-arylthi...