Background and aims of the study: Atopic dermatitis is a chronic inflammatory skin disorder that frequently involves some ophthalmic features. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is associated with the generation of cell-mediated immune responses. Although serum MIF levels may be elevated in severe atopic dermatitis, the quantity of MIF in regional oc...

Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in...

Background: No clinical clues to differentiate between extrinsic atopic dermatitis (eAD) and intrinsic atopic dermatitis (iAD). Aim: To compare presence of Pityriasis Alba (PA) in patients with extrinsic and intrinsic type of AD. Subjects & Methods: IL-4 and Ig-E were measured in 85 Patients’ serum with enzyme linked immune sorbent assay (ELISA). Forty three patients with (eAD) (group I) (n=43)...

BACKGROUND The yeasts of the genus Malassezia are members of the normal flora on human skin and they are found in 75~80% of healthy adults. Since its association with various skin disorders have been known, there have been a growing number of reports that have implicated Malassezia yeast in atopic dermatitis (AD). OBJECTIVE The aim of the present study is to isolate the various Malassezia spe...

pattern, atopic dermatitis (AD) affects individuals of all ages, although its prevalence is highest in children. While the pathophysiology of AD is not yet fully understood, genetically-based alterations in barrier function have recently been described, leading to enhanced understanding of the need to maintain the barrier function in this skin disorder. In light of these findings, barrier repai...

Abstract Atopic dermatitis (AD), or eczema, is a common skin disease that often associated with other atopic disorders, such as allergic rhinitis and asthma. The can develop both in infancy adulthood, characterizes recurrent episodes impairing the quality of life. review аnalyzes genetical, immunological, environmental factors pathogenesis AD. role barrier function also considered regard main h...

Atopic Dermatitis (AD) has a great impact on the lives of patients and their caregivers. Topical corticosteroids (TCS) are mainstay treatment, topical calcineurin inhibitors can be used ...

Quantification of quality of life (QOL) related to disease severity is important in patients with atopic dermatitis (AD), because the assessment provides additional information to the traditional objective clinical scoring systems. To document the impact of AD on QOL for both children and adults as well as to quantify the relationship with disease severity, QOL assessments were performed over a...

BACKGROUND Atopic dermatitis (AD) is an inflammatory skin condition that can occur in early life, predisposing to asthma development in a phenomenon known as the atopic march. Although genetic and environmental factors are known to contribute to AD and asthma, the mechanisms underlying the atopic march remain poorly understood. Filaggrin loss-of-function mutations are a major genetic predispose...

BACKGROUND Atopic dermatitis (AD) is a common skin disorder of increasing prevalence. Many ophthalmologic conditions are associated with AD, including cataract formation. Posterior and anterior subcapsular cataracts have been described in AD. Topical and systemic corticosteroids have been implicated in the development of cataracts. The precise pathogenic mechanisms and risk factors for developm...