Abstract In this study, the hemolymph vascular system (HVS) in two cambarid crayfishes, i.e. Marbled Crayfish, Procambarus virginalis Lyko, 2017 and Spiny Cheek Faxonius limosus (Rafinesque, 1817), is investigated regard of areas non-genetic phenotypic variation. Despite their genetic identity, specimens P. show variability certain features HVS. Thus, we describe varying branching patterns, spo...