when pooled immunoglobulin g (igg) from patients with multiple sclerosis (ms) was used to probe a human fetal spinal cord λgt 11 cdna library, the igg was found to bind to a predicted epitope of human mitochondrial nd4 sequence. to investigate the involvement of the nd4 as an autoantigen in ms, we determined the presence of specific antibody in the serum of ms patients and serum samples of some...

conclusions components of social support, totally account for 19% of resiliency variance value of patient; the components of social support, family, friends, and other people’s support at only had lower contribution in predicting resiliency. support of this group of people to increase their resiliency seems necessary. results there was a significant association between social support and resili...

background: multiple sclerosis (ms) is a chronic disease characterized by degradation of the central nervous system myelin which may impair the balance of patients. core stability exercises have been the focus of attention for repairing the stability of some patients.   objectives: to assess the effect of core stability exercise on the balance of patients with multiple sclerosis. materials and ...

background:  multiple  sclerosis  (ms) is a  chronic inflammatory  demyelinating  and  neurodegenerative disease  of central  nervous  system  with unknown  causes. etiology of ms involves  both  genetic  and  environment factors.  the  interleukin  7   receptor   (il7r)   gene   is  a promising candidate  for ms, because its involvement in the autoimmunity, regulation of the t-cell homeostasis...

OBJECTIVES Cognitive problems in multiple sclerosis are common but any possible benefits of treatment remain uncertain. The aim of the study was to evaluate the benefits of providing a psychology service, including cognitive assessment and intervention, to patients with multiple sclerosis. METHOD The study was a single blind randomised controlled trial. A total of 240 patients with clinically...

abstract background: fatigue is the most common and highly disabling symptom of multiple sclerosis (ms) that has negative effects on employment, the process of socialization, compliance with the disease, and other factors effective on activities of daily living. the usage of complementary and alternative medicine methods in ms patients is higher than in the general population. however, there is...

background: mesenchymal stem cells (mscs) with their potential to differentiate into mesodermal and non-mesodermal lineages have several immunomodulatory characteris-tics. these properties make them promising tools in cell and gene therapy. objective: to evaluate the potential therapeutic applications of autologous msc in improving clinical manifestations of ms patients. methods: ten patients w...

multiple sclerosis (ms) and migraine are two common neurological disorders affecting women more than men. sleep quality impairment has been reported in both diseases. the goal of this study was to compare sleep quality and depression between women with ms and migraine. seventy women with migraine and 75 women with ms were enrolled in this study. participants were asked to fill-out valid and rel...

none of the approved immunomodulatory drugs in adults multiple sclerosis (ms) patients have been officially approved for the pediatric patients and are currently used off-label in this population. in this study, we evaluated the effectiveness and tolerability of intramuscular interferon beta1-a (avonex®) and subcutaneously injected interferon beta1-b (betaferon®) in children with definite relap...