Air and moisture stable homoleptic bis(diimidazolylidine)nickel(II) complexes, ([(diNHC)(2)Ni](2+)) 3a,b and their corresponding silver(I) 4a,b and palladium(II) 5a,b complexes were synthesized and characterized by NMR and single crystal X-ray analysis. The catalytic potential of complex 3a was assessed in Mizoroki-Heck and Suzuki-Miyaura coupling reactions. In the Suzuki-Miyaura coupling react...

Aryl-aryl bond formation constitutes one of the most important subjects in organic synthesis. The recent developments in direct arylation reactions forming aryl-aryl bond have emerged as very attractive alternatives to traditional cross-coupling reactions. Here, we describe a general palladium-catalyzed direct arylation and cyclization of o-iodobiaryls to build a library of tetraphenylenes. Thi...

First-row metal complexes often undergo undesirable one-electron redox processes during two-electron steps of catalytic cycles. We report the amination of aryl chlorides and bromides with primary aliphatic amines catalyzed by a well-defined, single-component nickel precursor (BINAP)Ni(η(2)-NC-Ph) (BINAP = 2,2'-bis(biphenylphosphino)-1,1'-binaphthalene) that minimizes the formation of Ni(I) spec...

CdO nanoparticles efficiently catalyzes the condensation of aromatic aldehydes with 2-aminophenol at room temperature to afford 2-aryl benzoxazole derivatives by grinding method. The reactions proceed under heterogeneous and mild conditions to provide 2-aryl benzoxazoles in excellent yields (87-97 %) with high purity under solvent free condition. The reaction requires short time (5-23 minutes) ...

6-Carbethoxy-5-(3'-bromophenyl)-3-aryl-2-cyclohexenones 2a-j were obtained from the1-Aryl-3-(3'-bromophenyl)-2-propene-1-ones 1a-j by Micheal addition of ethyl acetoacetate, followed by internal Claisen condensation. Reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-Aryl-4-(3'-bromophenyl)-3-oxo-2,3a,4,5-tetrahydro-2H-indazoles 3a-j. The structures of newly synthesized compou...

New efficient synthetic methods in pyrazoline and pyrazolopyrazine chemistry have been developed starting from 2,2-dichlorovinylacetophenones 1, which were sequentially transformed into 3-aryl-5-dichloromethyl-1-(2-hydroxiethyl)-2-pyrazolines 2, 3-aryl-5-dichloromethyl-1-(2-O-tosylhydroxyethyl)-2-pyrazolines 3, 3-aryl-5-dichloromethyl-1-(2-azidoethyl)-2-pyrazolines 4, 3-aryl-5-dichloromethyl-1-...

Abstract N-Aryl-1,2,3,4-tetrahydroisoquinolines are obtained via a convenient and short protocol with broad range of substituents on both aromatic rings high functional group tolerance. Starting from readily available ortho-brominated aldehydes primary amines, condensation these building blocks under reductive conditions gives N-aryl 2-bromobenzylamines. The C-3/C-4-unit the tetrahydroisoquinol...

The stable phosphonate derivatives have easily synthesized by the reactions involving trialkyl(aryl) phosphites and dimethyl acetylenedicarboxylate in the presence of 4-nitrophenol and/or acid chlorides, dialkyl(aryl) phosphites and N-methylimidazole at 70 oC under solventfree conditions.

An efficient synthesis of novel 1-aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-ones from indoles and 1-aryl-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one using a Brønsted acid ionic liquid [Sbmim][HSO4] as catalyst is described. Satisfactory results with excellent yields and short reaction time were obtained in the experiments. The catalyst could be recovered conveniently and reused e...

Density functional theory has been used to investigate various solvated species that may be formed from palladium bis N-heterocyclic carbene complexes, [Pd(cyclo-C{NRCH}2)2], (PdL2) in benzene solution. Formation of an g -arene complex is shown to stabilise a monocarbene species, PdL(g-C6H5X), where the arene is either the solvent or a reacting aryl halide. Oxidative addition of an aryl chlorid...