Background & Aims: In most cases, drugs used for the treatment of cancer are not effective or have unpleasant side-effects. This has forced scientists to find more effective drugs with less toxicity. Artemisia is an important medicinal plant in the world and anti-tumoral activity of some Artemisia species has been reported. This study was designed for evaluation of anti-tumoral effect of methan...

BACKGROUND The aim of this study was to investigate the 'acaricidal effect' of Zataria multiflora and Artemisia annua essential oils on Rhipicephalus (Boophilus) annulatus. METHODS This study was carried out in 2009 in the Laboratory of Parasitology of the Faculty of Veterinary Medicine of Shahrekord University, west central Iran. Six dilutions (5, 10, 20, 40, 60 and 80 µL/cm(3)) of both esse...

Artemisinin (quinghaosu) is a natural compound, isolated from Artemisia annua L. (Compositae), of current interest in treatment of drug-resistant malaria. Aim of the current study was to hit upon novel artemisinin sources as alternative to A. annua. Therefore, ten species of the genus Artemisia (A. santonicum L., A. taurica Willd., A. spicigera K. Koch, A. herba-alba Asso, A. haussknechtii Bois...

Four new compounds obtained from cultured cells of Artemisia annua were reported. Products were detected by HPLC-ELSD/GC-MS and isolated by chromatographic methods. The structures of four new compounds, namely 6-hydroxy arteannuin I (1), 1-hydroxy arteannuin I (2), 2-hydroxy arteannuin J (3), and 14-hydroxy arteannuin J (4), were elucidated using their physico-chemical properties by NMR and MS ...

In our ongoing investigation into Artemisia annua for the treatment of malaria, we decided to study the possibility that synergism might enhance the efficacy of artemisinin. Our main objective was to test tea infusions and nonpolar extracts prepared from different A. annua varieties against Plasmodium falciparum in vitro in order to determine if synergism will increase the effectiveness of arte...

In the study we focus on determining the contents of artemisinin in Artemisia annua L. from different geographical origins of southwest district of China. The artemisinin contents of eleven samples are measured by the high performance liquid chromatography (HPLC). As a result, Artemisinin exists in different parts of A. annua plant and the content is as follow: inflorescences > leaves > stems. ...

Sweet potato is known to be rich in healthful antioxidants, but the stability of its antioxidant properties under gastrointestinal pH is very much unknown. Hence, this study aimed to evaluate the changes in antioxidant properties (total contents of phenolics and flavonoids as well as antioxidant activity) of sweet potato flour (SPF) under simulated gastrointestinal pH conditions. It was found t...

BACKGROUND In addition to recognized antimalarial effects, Artemisia annua L. (Qinghao) possesses anticancer properties. The underlying mechanisms of this activity are unknown. The aim of our experiments was to investigate the effects of distinct types of compounds isolated from A. annua on the immune-activated production of major mediators of angiogenesis playing a crucial role in growth of tu...

Endophytic actinobacteria colonize internal tissues of their host plants and are considered as a rich and reliable source of diverse species and functional microorganisms. In this study, endophytic actinobacterial strain YIM 63111 was isolated from surface-sterilized tissue of the medicinal plant Artemisia annua. We identified strain YIM 63111 as a member of the genus Pseudonocardia. A. annua s...

Objective: This review intends to motivate and encourage researchers to explore new alternatives to treat different diseases with Artemisia annua L., an important plant of traditional Chinese pharmacopoeia that has been used for more than 2.000 years in the treatment of different diseases, mainly malaria. Methods: Data include currently available information about A. annua, its origin, traditio...