The β2-adrenergic effects of macerated extract, aqueous extract, ethanol extract, and essential oil of Carum copticum, 5 nM propranolol, and saline were tested by performing cumulative Log concentration-response curves of isoprenaline-induced relaxation of precontracted isolated guinea pig tracheal chains in three different conditions including: non-incubated (group 1, n=9) incubated with 1...

BACKGROUND Plant polyphenols are known for their limiting of adverse effects on reactive oxygen species (ROS) in biological systems. The photochemiluminescence (PCL) assay allows to evaluate the antiradical activity of a compound in the presence of a superoxide anion-radical (O •-), which is one of the ROS directly associated with the human body. In this work, determination of the superoxide an...

Background and objectives: The seedsof Sophora alopecuroides L. var. alopecuroides may benefit treatment of opioid dependence. Therefore, the plant alkaloid composition, toxicity and effects on morphine withdrawal were studied. Methods: The alkaloid composition was determined by GC and GC/MS analysis. Mice were made dependent by morphine injec...

The ethanol and aqueous extracts of leaves of Neptunia Oleracea lour (Mimosaceae) were tested for their efficacy against carbon tetrachloride (CCl4) induced hepatotoxicity in Wistar albino rats. The different groups of animals were administered ethanol and aqueous extracts to carbon tetrachloride treated rats. In the present study ethanol extract (p<0.01) and aqueous extract (p<0.05) significan...

BACKGROUND Moringa stenopetala has been used in traditional health systems to treat diabetes mellitus. The aim of this study was to investigate the antidiabetic activity of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin (STZ) induced diabetic rats. METHODS The aqueous ethanol extract and n-butanol fraction of Moringa stenopetala leaves hydroalcoholic (5...

The leaves of Acalypha wilkesiana are eaten as vegetables as part of the traditional management of hypertension in Nigeria. This study was therefore conducted to evaluate the implications of oral administration of extracts of Acalypha wilkesiana leaves, on serum electrolytes, urea and creatinine, in normal experimental rabbits. A total of eighteen (18) rabbits were randomized into three groups ...

Objective: Present investigations were carried out for evaluation of antitumor and in vitro antioxidant activity of ethanol and aqueous extracts of Jasminum angustifolium Linn. Methods: For its antitumor activity, Ehrlich ascites carcinoma (EAC) induced swiss albino mice were used and were divided into five group with 6 animal each.The antitumor effect was assessed using viable tumour cell coun...

Successive solvent extract viz., petroleum ether, chloroform, methanol, ethanol and water extracts of bark of Betula utilis D. Don was evaluated for antibacterial activity, against fourteen important bacterial strains by agar-well diffusion method. Methanol extract was showed significant activity against all the tested bacteria followed by ethanol and aqueous extract. Chloroform and Petroleum e...

BACKGROUND Ajuga remota Benth is traditionally used in Ethiopia for the management of diabetes mellitus. Since this claim has not been investigated scientifically, the aim of this study was to evaluate the antidiabetic effect and phytochemical screening of the aqueous and 70% ethanol extracts on alloxan-induced diabetic mice. METHODS After acute toxicity test, the Swiss albino mice were induc...